13039-56-0

Basic information

• Product Name: 5-DEOXY-L-ARABINOSE
• Synonyms: 5-DEOXY-L-ARABINOSE;5-Methyl-tetrahydro-furan-2,3,4-triol;L-5-Deoxyarabinose;5-Deoxy-L-arabinosone;L-Arabinose, 5-deoxy-;(2R,3S,4S)-2,3,4-trihydroxypentanal
• CAS NO: 13039-56-0
• Molecular Formula: C₅H₁₀O₄
• Molecular Weight: 134.1305
• EINECS: 1533716-785-6
• Product Categories: Carbohydrates & Derivatives
• Mol File: 13039-56-0.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 294.479 °C at 760 mmHg
• Flash Point: 146.128 °C
• Appearance: /
• Density: 1.315 g/cm³
• Refractive Index: 1.565
• Storage Temp.: Hygroscopic, Refrigerator, under inert atmosphere
• Solubility: DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
• CAS DataBase Reference: 5-DEOXY-L-ARABINOSE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-DEOXY-L-ARABINOSE(13039-56-0)
• EPA Substance Registry System: 5-DEOXY-L-ARABINOSE(13039-56-0)

Safety Data

• Hazardous Substances Data: 13039-56-0(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 13039-56-0 differently. You can refer to the following data:
1. Shows strong inhibitory effect -galactosidase of Escherichia coli.
2. Shows strong inhibitory effect β-galactosidase of Escherichia coli.

InChI:InChI=1/C5H10O4/c1-2-3(6)4(7)5(8)9-2/h2-8H,1H3/t2-,3?,4+,5?/m0/s1

Upstream product

• 3615-41-6 L-Rhamnose 
• 24807-89-4 2,3,4,5-tetra-O-acetyl-L-rhamnose diethyl dithioacetal 
• 6748-70-5 L-rhamnose diethyl dithioacetal 
• 13039-79-7 5-tosyl-L-(+)-arabinose-diethylmercaptal 
• 488-28-8 L-rhamnitol 
• 7732-18-5 water 
• 93978-95-1 5-deoxy-α-L-arabinose 
• 54253-49-5 1,1-diethylsulfonyl-L-rhamnose 
• 82970-19-2 (2S,3S,4S)-6,6-bis(ethylsulfonyl)-hex-5-ene-2,3,4-triol 
• 132130-06-4 L-arabino-3,4,5-triacetoxy-1,1-bis-ethanesulfonyl-hex-1-ene 
• 5328-37-0 L-arabinose 
• 43179-48-2 L-arabinose di(ethylthio)acetal 
• 93978-94-0 5-deoxy-β-L-arabinose 
• 13039-80-0 5-deoxy-L-(+)-arabinose-diethylmercaptal 

Downstream Products

• 22150-76-1 biopterin 
• 76647-70-6 (3R,4R,5S)-3,4-dihydroxy-5-methyldihydrofuran-2(3H)-one 
• 2636-52-4 L-Primapterin 
• 94591-31-8 2-N-Benzoyl-1',2'-di-O-benzoyl-4-thiobiopterin 
• 94591-29-4 2-N-Benzoyl-1',2'-di-O-benzoylbiopterin 
• 94591-24-9 Biolumazin 
• 5531-26-0 L-erythro-5-deoxy-[2]pentosulose-bis-(4-bromo-phenylhydrazone) 
• 13039-60-6 L-erythro-5-deoxy-[2]pentosulose-bis-phenylhydrazone 
• 62933-57-7 1',2'-O-diacetyl-L-biopterin 
• 95895-36-6 5-deoxy-2,3,4-O-triacetyl-L-arabinose-phenylhydrazone 
• 59245-36-2 (2S,3S,4S)-1-(Phenyl-hydrazono)-pentane-2,3,4-triol 
• 59245-36-2 5-deoxy-L-arabinose phenylhydrazone 
• 93978-94-0 5-deoxy-β-L-arabinose 
• 93978-95-1 5-deoxy-α-L-arabinose 

Relevant articles and documents

Pterin chemistry: A simple synthesis of 5-deoxy-L-[5-2H1]arabinose and L-[3'-2H1]biopterin

A simple synthesis of 5-deoxy-L-[5-2H1]arabinose was performed to obtain L-[3'-2H1]biopterin. The reduced form of this model substance is needed to investigate the pathway of 7-substituted pterins in patients with primapterinuria.

COMPOSITIONS AND METHODS FOR THE TREATMENT OF METABOLIC DISEASES

The invention relates to the compounds of formula I, formula II and formula III or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula I, formula II or formula III; and methods for treating or preventing metabolic diseases may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, intravenous, parenteral administration, syrup, or injection. Such compositions may be used to treatment of phenylketonuria, cardiovascular disease, autism, ADHD, hypertension, endothelial dysfunction and chronic kidney disease.

PROCESS FOR THE PREPARATION OF PTERIDINE DERIVATIVES

The application discloses a process for the preparation of 5-deoxy-L-arabinose of formula (VI); comprising the conversion of a compound of formula (XII); wherein n is 0, 1 or 2; which can be used as intermediate for the synthesis of sapropterin.