1303973-25-2Relevant articles and documents
PYRIDO[3,4-B]PYRAZINE DERIVATIVES AS SYK INHIBITORS
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Paragraph 0639; 0640; 0641, (2014/02/15)
A compound of formula (I): or a salt thereof; which is an inhibitor of spleen tyrosine kinase (Syk) and therefore potentially of use in treating diseases resulting from inappropriate activation of mast cells, macrophages, and B-cells and related inflammatory responses and tissue damage, for instance inflammatory disease and/or allergic disorders, and in cancer therapy, specifically heme malignancies, and autoimmune conditions.