13040-77-2

Basic information

• Product Name: 6-CHLORO-2,2'-BIPYRIDINE
• Synonyms: 6-CHLORO-2,2'-BIPYRIDINE;2-CHLORO-2,2'-BIPYRIDINE;6-Chloro-2,2'-bipyridyl;2-chloro-6-(pyridin-2-yl)pyridine
• CAS NO: 13040-77-2
• Molecular Formula: C₁₀H₇ClN₂
• Molecular Weight: 190.63
• Mol File: 13040-77-2.mol
• Article Data: 20

Chemical Properties

• Melting Point: 62℃
• Boiling Point: 320.6±27.0 °C(Predicted)
• Appearance: /
• Density: 1.245±0.06 g/cm3 (20 ºC 760 Torr)
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 3.72±0.22(Predicted)
• CAS DataBase Reference: 6-CHLORO-2,2'-BIPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-CHLORO-2,2'-BIPYRIDINE(13040-77-2)
• EPA Substance Registry System: 6-CHLORO-2,2'-BIPYRIDINE(13040-77-2)

Safety Data

• Hazardous Substances Data: 13040-77-2(Hazardous Substances Data)

Usage

General Description

6-CHLORO-2,2'-BIPYRIDINE is a chemical compound with the molecular formula C10H7ClN2. It is a derivative of bipyridine, containing a chlorine atom attached to the 6-position of the molecule. 6-CHLORO-2,2'-BIPYRIDINE is commonly used as a ligand in coordination chemistry, particularly in the field of organometallic chemistry and catalysis. Its structure and properties make it a versatile ligand for coordinating with various metal ions, allowing for the development of novel catalysts and materials. Additionally, 6-CHLORO-2,2'-BIPYRIDINE has also been investigated for its potential pharmaceutical applications, particularly in the development of new drugs. Overall, this chemical compound has a wide range of applications in the fields of chemistry and materials science.

Upstream product

• 33421-43-1 2,2'-bipyridyl N-oxide 
• 109-09-1 2-chloropyridine 
• 366-18-7 [2,2]bipyridinyl 
• 2402-78-0 2,6-dichloropyridine 
• 17997-47-6 2-tri-n-butylstannylpyridine 
• 108-86-1 bromobenzene 
• 5140-72-7 2-bromo-6-chloro-pyridine 
• 109-04-6 2-bromo-pyridine 
• 652148-92-0 2-chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine 
• 101001-90-5 <2,2'-bipyridin>-6(1H)-one 
• 5029-67-4 2-iodopyridine 
• 77972-47-5 1-methyl-2-(2′-pyridyl)pyridinium iodide 
• 263698-99-3 2-chloro-6-(tributylstannyl)pyridine 
• 154928-15-1 1-methyl-2,2'-bipyridine-6-one 

Downstream Products

• 152194-39-3 6-(diphenylphosphino)-2,2'-bipyridine 
• 4392-83-0 2,2':6',2'':6'',2'''-quaterpyridine 
• 178039-84-4 6-amino-2-2’-pyridylbipyridine 
• 10495-73-5 2-bromo-6-(pyridin-2-yl)pyridine 
• 135853-33-7 6-(1H-pyrazol-1-yl)-2,2'-bipyridine 
• 239798-76-6 6-mercapto-2,2'-bipyridine 
• 942274-96-6 6-(2-acetylphenyl)-2,2'-bipyridine-5-carboxylic acid ethyl ester 
• 1200396-63-9 ethyl 2,3,4-tri-O-benzyl-6-O-(2,2'-bipyridin-6-yl)-1-thio-β-D-glucopyranoside 
• 1192424-21-7 C₂₂H₂₈N₄O₂S 
• 1223063-81-7 6-fluoro-2,2′-bipyridine 

Relevant articles and documents

Novel DNA binding agents: Hydrazone-based helical trinuclear Ag complexes

Using the hydrazone linker and the self-assembly, functionalized Ag complexes with a helical structure showed a 2.96 A distance between metal-metal bonds, well-aligned aromatic rings, and the strong affinity toward DNA.

Micelle-Enabled Suzuki-Miyaura Cross-Coupling of Heteroaryl Boronate Esters

We report a micellar protocol for Suzuki-Miyaura cross-coupling of heteroaryl boronic esters with aryl or heteroaryl halides. The micellar catalysis enables this coupling reaction to run under mild conditions, which avoids the decomposition of heteroaryl boronate esters and allows for high chemoselectivity for cross-coupling reaction with 6-chloropridine-2-boronic ester. The micellar protocol expands the scope of the cross-coupling reaction with challenging heteroaryl boronic esters and complements the existing cross-coupling methods for construction of heterobiaryl building blocks.

METHOD FOR COUPLING HALOGENATED PYRIDINE COMPOUND WITH HALOGENATED AROMATIC COMPOUND

There is a demand for the development of a technique according to which a reaction for coupling a halogenated pyridine compound with a halogenated aromatic compound can be performed in a simple manner through a small number of steps without using expensive agents such as a palladium catalyst. A method for coupling a halogenated pyridine compound with a halogenated aromatic compound includes a step of coupling a halogenated pyridine compound with a halogenated aromatic compound to obtain a pyridine compound by reacting, in a reaction solvent, the halogenated pyridine compound and the halogenated aromatic compound with a solution containing an alkali metal.