130426-99-2Relevant academic research and scientific papers
Tin (IV) chloride-promoted synthesis of 4-aminopyridines and 4-aminoquinolines
Veronese, Augusto C.,Callegari, Rosella,Morelli, Carlo F.
, p. 12277 - 12284 (2007/10/02)
Ortho-aminobenzonitriles 1 react with β-ketoesters and alkyl malonates, in the presence of stoichiometric amounts of tin (IV) chloride, to give 4-aminoquinolines 2 and 4-amino-2-quinolones 3 respectively. Similarly β-enaminonitriles 7 afford 4-aminopyridi
Tin (IV) chloride-promoted reactions of β-dicarbonyl compounds with nitriles. Synthesis of aminopyridines and aminoquinolines
Veronese, Augusto C.,Callegari, Rosella,Salah, Suada Ahmed Ali
, p. 3485 - 3488 (2007/10/02)
β-Ketoesters and β-diesters react with β-enaminonitriles in the presence of stoichiometric amounts of tin (IV) chloride to give 4-aminopyridines and pyridones while they react with aromatic orthoaminonitriles to give 4-aminoquinolines and quinolones.
