15595-71-8Relevant articles and documents
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Brown
, p. 326 (1975)
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Catalytic Reductive Synthesis and Direct Derivatization of Unprotected Aminoindoles, Aminopyrroles, and Iminoindolines
Leijendekker, Leonardus H.,Weweler, Jens,Leuther, Tobias M.,Streuff, Jan
supporting information, p. 6103 - 6106 (2017/05/22)
A titanium(III)-catalyzed radical cyclization to unprotected 3-aminoindoles, 3-aminopyrroles, or 3-iminoindolines is reported. The reaction is non-hazardous, scalable, and allows facile isolation of the free products by extraction. The method is demonstrated on a large substrate scope and it further allows the direct installation of various nitrogen protecting groups or the synthesis of building blocks for peptide chemistry in a single sequence. Fused bisindoles can be directly accessed from the cyclization products.
Diverse tandem cyclization reactions of o -cyanoanilines and diaryliodonium salts with copper catalyst for the construction of quinazolinimine and acridine scaffolds
Pang, Xinlong,Chen, Chao,Su, Xiang,Li, Ming,Wen, Lirong
supporting information, p. 6228 - 6231 (2015/01/09)
Two cyclization modes are realized to produce different nitrogen-containing heterocycles, i.e.; quinazolin-4(3H)-imines and acridines by assembling o-cyanoanilines and diaryliodonium salts via tandem reaction pathways.
Rhodium-catalyzed asymmetric hydrogenation of β-acetylamino acrylonitriles
Ma, Miaofeng,Hou, Guohua,Wang, Junru,Zhang, Xumu
experimental part, p. 506 - 511 (2011/06/17)
The rhodium-catalyzed asymmetric hydrogenation of β-acetylamino acrylonitriles was investigated by using monophosphine and bisphosphine ligands. It was found that an Rh-QuinoxP complex exhibited high enantioselectivities for β-aryl substituted β-acetylamino acrylonitriles and the Rh-JosiPhos CyPF-t-Bu complex was proven to be effective for the hydrogenation of tetrasubstituted olefins from cyclic β-acetylamino acrylonitriles.