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Upstream product

• 702-23-8 2-(4-Methoxyphenyl)ethanol 
• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 
• 993-07-7 trimethylsilan 
• 201230-82-2 carbon monoxide 
• 104-21-2 p-methoxybenzyl acetate 

Relevant academic research and scientific papers

An asymmetric Salamo-based Zn complex supported on Fe3O4MNPs: a novel heterogeneous nanocatalyst for the silyl protection and deprotection of alcohols under mild conditions

In this study, a magnetic asymmetric Salamo-based Zn complex (H2L = salen type di-Schiff bases)-supported on the surface of modified Fe3O4(Fe3O4@H2L-Zn) as a new catalyst was designed and characterizedvianumerous analytical techniques such as FT-IR spectroscopy, XRD, EDS, ICP-AES, SEM, TEM, TGA and VSM. An efficient and sustainable synthetic protocol has been presented for the synthesis of silyl ether substructuresviathe silyl protection of alcohols under mild conditions. The synthetic protocol involves a two-component solvent-free reaction between various hydroxyl-bearing substrates and hexamethyldisilazane (HMDS) as an inexpensive silylating agent using Fe3O4@H2L-Zn MNPs as a magnetically separable, recyclable and reusable heterogeneous catalyst. Fe3O4@H2L-Zn MNPs were also applied for the removal of silyl protecting groups from hydroxyl functions using water in CH2Cl2under green conditions. The catalyst demonstrated good to excellent catalytic yield efficiency for both the reactions compared to the commercial metal-based catalysts under green conditions for a wide range of substrates.

Cross-linked poly(4-vinylpyridine/styrene) copolymer-supported bismuth(III) triflate: An efficient heterogeneous catalyst for silylation of alcohols and phenols with HMDS

Cross-linked poly(4-vinylpyridine/styrene) copolymer-supported bismuth(III) triflate (30P/S-Bi) effectively activates hexamethyldisilazane (HMDS) for the silylation of alcohols and phenols. By the use of this heterogeneous catalytic system, a wide range of alcohols as well as phenols are converted into their corresponding trimethylsilyl ethers in high yield under mild reaction conditions. The catalyst was reused more than 10 times without significant loss of its catalytic activity.

Catalyst-free silylation of alcohols and phenols by promoting HMDS in CH3NO2 as solvent

An uncatalyzed method for the silylation of alcohols and phenols with HMDS in CH3NO2 at rt is developed. A diverse range of aromatic and aliphatic alcohols as well as phenols undergo the silylation in very short reaction time with ex

Mild and efficient silylation of alcohols and phenols with HMDS using Bi(OTf)3 under solvent-free condition

A very efficient and mild silylation of alcohols and phenols with hexamethyldisilazane (HMDS) at rt is developed using Bi(OTf)3 as the catalyst. Primary, secondary and tertiary alcohols as well as phenols are excellently converted into correspo

Nafion SAC-13: heterogeneous and reusable catalyst for the activation of HMDS for efficient and selective O-silylation reactions under solvent-free condition

Nafion SAC-13 effectively activates hexamethyldisilazane (HMDS) for the efficient and selective silylation of alcohols. Primary, secondary, and tertiary alcohols and phenols are efficiently converted to their corresponding silylethers in short reaction ti

Co2(CO)8-Catalyzed Reaction of Benzylic Acetates with HSiMe3 and CO. A Novel Method for Homologation of Alcohols

In the presence of Co2(CO)8, the reaction of benzyl acetates with HSiMe3 and carbon monoxide under mild reaction conditions (25 deg C, 1 atm of CO) resulted in the incorporation of CO to give β-phenethyl alcohols.The reaction is applicable to naphthyl-, furanyl-, thiophenyl-, and even ferrocenyl methyl acetates.