13044-42-3

Usage

Uses

Used in Pharmaceutical Industry:
Pyrrolidine, 1-(1E)-1-propenylis utilized as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure and reactivity allow for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
Pyrrolidine, 1-(1E)-1-propenylalso finds application in the agrochemical sector, where it serves as a building block for the creation of novel agrochemicals, contributing to the development of more effective and environmentally friendly products for agricultural use.
Used in Organic Synthesis:
Pyrrolidine, 1-(1E)-1-propenylis employed as a versatile building block in organic synthesis, enabling the production of a wide range of organic compounds for various applications, including but not limited to materials science, specialty chemicals, and research reagents.
Overall, Pyrrolidine, 1-(1E)-1-propenylis a valuable chemical intermediate with diverse applications across multiple industries, primarily due to its unique structure and reactivity in organic chemistry.

Upstream product

• 123-75-1 pyrrolidine 
• 123-38-6 propionaldehyde 
• 24420-11-9 1-allyl-pyrrolidine 

Downstream Products

• 97130-10-4 2,4-dimethyl-5-oxo-5-phenyl-3-pentenoic acid pyrrolidinamide 
• 13808-62-3 4-methyl-3-phenyl-1H-pyrazole 
• 100-52-7 benzaldehyde 
• 97130-07-9 benzoyl-N-pyrrolidinoformamide-benzoylhydrazone 
• 97130-06-8 {[(E)-2-Methyl-1-phenyl-3-pyrrolidin-1-yl-prop-2-en-(E)-ylidene]-hydrazono}-phenyl-acetic acid 
• 97130-08-0 E- and Z-2,4-dimethyl-5-oxo-5-phenyl-2-pentenoic acid pyrrolidinamide 

Relevant academic research and scientific papers

HETEROAROMATIC COMPOUNDS HAVING SPHINGOSINE-1-PHOSPHATE (S1P) RECEPTOR AGONIST BIOLOGICAL ACTIVITY

A novel compound having agonist activity at the S1P3 receptor which is represented by the formula I wherein X is selected from the group consisting of CR3, N and NO;Y is selected from the group consisting of CR3, N and NO;Z is selected from the group consisting of CR3, N and NO; and at least one of X, Y and Z is N or NO; V is O or NOR4 R1 is an aryl group;R2 is an aryl group;R3 is selected from the group consisting of H and alkyl; and 2 of said R3 groups may together form a cyclic alkyl ring having from 3 to 6 carbon atoms; R4 is selected from the group consisting of H and alkyl;a is 0 or an integer of from 1 to 6;b is 0 or 1;c is 0 or 1;f is 0 or an integer of 1 or 2;x is 0 or 1;y is 0 or an integer of from 1 to 3; andz is 0 or an integer of from 1 to 3.

MOLECULARLY IMPRINTED POLYMERS SELECTIVE FOR NITROSAMINES AND METHODS OF USING THE SAME

A class of molecularly imprinted polymers that specifically recognizes and binds to nitrosamines members of which class are useful, for example, in analysis and separation of nitrosamines from biological fluids. Such molecularly imprinted polymers are also useful in methods of treating and manufacturing tobacco products and materials.

Regioselective Synthesis of 6-Alkylated Lumazine Derivatives

The regiospecific synthesis of alkylated lumazines is achieved by hetero Diels-Alder addition between an oxadiazinone 2 and enamine.The reactions proceed stepwise by cycloaddition, decarboxylation and deamination to produce the 6-alkylated lumazines.

ISOMERIZATION AND HYDROGENATION OF NITROGEN-CONTAINING ORGANIC COMPOUNDS CATALYZED BY HETEROGENOUS CATALYSTS

The double-bond isomerization of 1-N-pyrrolidino-2-propene ( -> ) and N,N-dimethyl-2-propenylamine ( -> ) were studied at 40 deg C over MgO, CaO, SrO, BaO, La2O3, ThO2, ZrO2, ZnO etc.It was found that MgO and CaO which have strong basic sites on the surfaces exhibited a high catalytic activity, the selectivity for the formation of 1-N-pyrrolidino-1-propene being more than 80percent.The double-bond migration of the the allylamines is suggested to proceed via anionic intermediates in which the cis form is much more stable than the trans form.For the hydrogenation of N,N-dimethyl-2-propenylamine ( + H2 -> ), the activity as well as the selectivity of nickel catalysts supported on MgO, CaO, La2O3, ThO2, TiO2, ZrO2 etc. was examined at 0 deg C.Nickel on MgO was found to give 100 percent conversion and almost 100 percent selectivity for the formation of N,N-dimethyl-propenylamine.It is suggested that nickel catalyst becomes active when supported on basic oxides.The reaction path is discussed on the basis of experiments using deuterium as a tracer.