1304774-08-0

Basic information

• Product Name: (4S)-5-oxo-4-[[(phenylmethoxy)carbonyl]amino]-5-[(2-phenylethyl)amino]pentanoic acid
• CAS NO: 1304774-08-0
• Molecular Weight: 384.432
• Mol File: 1304774-08-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4S)-5-oxo-4-[[(phenylmethoxy)carbonyl]amino]-5-[(2-phenylethyl)amino]pentanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (4S)-5-oxo-4-[[(phenylmethoxy)carbonyl]amino]-5-[(2-phenylethyl)amino]pentanoic acid(1304774-08-0)
• EPA Substance Registry System: (4S)-5-oxo-4-[[(phenylmethoxy)carbonyl]amino]-5-[(2-phenylethyl)amino]pentanoic acid(1304774-08-0)

Safety Data

• Hazardous Substances Data: 1304774-08-0(Hazardous Substances Data)

Upstream product

• 23632-67-9 (S)-3-[3-(benzyloxycarbonyl)-5-oxooxazolidin-4-yl]propanoic acid 
• 64-04-0 phenethylamine 
• 1155-62-0 N-benzyloxycarbonyl-L-glutamic acid 
• 56-86-0 L-glutamic acid 

Downstream Products

• 121426-39-9 methyl (4S)-5-oxo-4-[[(phenylmethoxy)carbonyl]amino]-5-[(2-phenylethyl)amino]pentanoate 
• 1304774-09-1 phenylmethyl (3S)-[2,6-dioxo-1-(2-phenylethyl)-3-piperidinyl]carbamate 
• 1175950-31-8 C₁₃H₁₆N₂O₂ 
• 492-87-5 N-[(3S)-2,6-dioxo-1-(2-phenylethyl)-3-piperidinyl]-(2S)-2-methylbutanamide 

Relevant articles and documents

Synthesis of N -[(3 S)-2,6-dioxo-1-(2-phenylethyl)-3-piperidinyl]-(2 S)-2-methylbutanamide (( - )-julocrotine)

The total synthesis of ( - )-julocrotine (1) starting from l-glutamic acid in 41% overall yield is described. The methodology utilizes protection, deprotection, and regioselection (carbonyl differentiation via oxazolidinone) protocols, and glutarimide ring formation is the key step.