1304774-09-1Relevant articles and documents
Synthesis of (-)-julocrotine and a diversity oriented Ugi-approach to analogues and probes
Neves Filho, Ricardo A. W.,Westermann, Bernhard,Wessjohann, Ludger A.
, p. 1504 - 1507 (2012/01/06)
An improved total synthesis of (-)-julocrotine in three steps from Cbz-glutamine, in 51% overall yield, is presented. To demonstrate the potential of the heterocyclic moiety for diversity oriented synthesis, a series of (-)-julocrotine analogues was synthesized by employing the heterocyclic precursor as an amino input in Ugi four-component reactions (Ugi-4CR) [1].