13049-01-9

Basic information

• Product Name: GLYCINE N-PROPYL ESTER HYDROCHLORIDE
• Synonyms: PROPYL GLYCINATE HYDROCHLORIDE;GLYCINE N-PROPYL ESTER HYDROCHLORIDE;propyl aminoacetate hydrochloride;Glycinen-propylesterHCl;GlycinepropylesterHCl;Einecs 235-925-0;Propyl aminoacetate HCl;Propyl 2-aminoacetate hydrochloride
• CAS NO: 13049-01-9
• Molecular Formula: C₅H₁₁NO₂*ClH
• Molecular Weight: 153.61
• EINECS: 235-925-0
• Mol File: 13049-01-9.mol
• Article Data: 3

Chemical Properties

• Melting Point: 78-80°C
• Boiling Point: 135.1 °C at 760 mmHg
• Flash Point: 10.6 °C
• Appearance: /
• Density: 0.99g/cm³
• Vapor Pressure: 7.86mmHg at 25°C
• Refractive Index: 1.429
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: GLYCINE N-PROPYL ESTER HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: GLYCINE N-PROPYL ESTER HYDROCHLORIDE(13049-01-9)
• EPA Substance Registry System: GLYCINE N-PROPYL ESTER HYDROCHLORIDE(13049-01-9)

Safety Data

• Safety Statements: 22-24/25
• Hazardous Substances Data: 13049-01-9(Hazardous Substances Data)

Usage

General Description

Glycine N-propyl ester hydrochloride is a chemical compound that is derived from the amino acid glycine and is commonly used in organic synthesis and medicinal chemistry. It is a white crystalline solid that is soluble in water and alcohol, and it is often used as a reactant or reagent in various chemical reactions, particularly in the production of pharmaceuticals and agrochemicals. GLYCINE N-PROPYL ESTER HYDROCHLORIDE is also known for its role as a buffering agent and its ability to stabilize pH levels in certain formulations. Additionally, it has been studied for its potential pharmacological properties, including its anti-inflammatory and analgesic effects, making it a compound of interest for research and development in the pharmaceutical industry.

InChI:InChI=1/C5H11NO2/c1-2-3-8-5(7)4-6/h2-4,6H2,1H3

Upstream product

• 71-23-8 propan-1-ol 
• 6000-43-7 2-aminoethanoic acid hydrochloride 
• 56-40-6 glycine 

Downstream Products

• 81167-34-2 propyl 2-(diphenylmethyleneamino)acetate 
• 2979-59-1 propyl N-benzoyl-glycinate 
• 294177-64-3 propyl N-[3-phenyl-1-oxo-2-propen-1-yl] glycinate 

Relevant articles and documents

Synthesis and antimicrobial activities of novel sorbic and benzoic acid amide derivatives

A series of sorbic and benzoic acid amide derivatives were synthesized by conjugating sorbic acid (SAAD, a1–a7) or benzoic acid (BAAD b1–b6) with amino acid esters and their antimicrobial activities were investigated against Escherichia coli, Bacillus subtilis and Staphylococcus aureus, mixed bacteria from rancid milk, Saccharomyces cerevisiae, and Aspergillus niger. The antimicrobial activity of sorbic acid amides was better than that of benzoic acid amides. The minimum inhibitory concentrations (MIC) of compound isopropyl N-[1-oxo-2, 4-hexadien-1-yl]-L-phenylalaninate (a7) were 0.17 mM against B. subtilis, and 0.50 mM against S. aureus, while the MIC values of sorbic acid were more than 2 mM respectively. Also, compound a7 displayed pH-independent antimicrobial activity in the range of pH 5.0–9.0 and was effective at pH 9.0. These results demonstrated that the conjugation of sorbic acid with amino acid esters led to significant improvement of in vitro antimicrobial attributes, but little effect was observed for benzoic acid amide derivatives.

THIAZOLE DERIVATIVES AS SGLT2 INHIBITORS AND PHARMACEUTICAL COMPOSITION COMPRISING SAME

The present invention relates to a novel compound with thiazole ring having an inhibitory activity against sodium-dependent glucose cotransporter 2 (SGLT2) being present in the intestine and kidney, and a pharmaceutical composition comprising the same as an active ingredient, which is useful for preventing or treating metabolic disorders, particularly diabetes.