130495-83-9Relevant academic research and scientific papers
Building Blocks for Oligonucleotide Analogues with Dimethylene Sulfide, Sulfoxide, and Sulfone Groups Replacing Phosphodiester Linkages
Huang, Zhen,Schneider, K. Christian,Benner, Steven A.
, p. 3869 - 3882 (2007/10/02)
Two routes are presented for the synthesis of 3',5'-bishomodeoxyribonucleosides, building blocks needed to synthesize oligodeoxynucleotide analogues where the OPO2O groups are replaced by CH2SCH2, CH2SOCH2, and CH2SO2CH2 units.Two of these have been coupl
A Ring-Enlarged Oxetanocin A Analogue as an Inhibitor of HIV Infectivity
Tseng, Christopher K-H.,Marquez, Victor E.,Milne, George W. A.,Wysocki, Roland J.,Mitsuya, Hiroaki,et al.
, p. 343 - 349 (2007/10/02)
Two ring-expanded analogues (compounds 2 and 3) of the anti-HIV fermentation product oxetanocin A (1) were synthesized from commercially available diacetone D-glucose.Antiviral testing against HIV in ATH8 cells revealed that the ring-expanded analogue 2 p
