130516-29-9Relevant academic research and scientific papers
NEW STRATEGY FOR THE CONSTRUCTION OF CARBAPENEMS. TOTAL SYNTHESIS OF 6-epi PS-5 AND PS-5
Koskinen, Ari M. P.,Ghiaci, Mehran
, p. 3209 - 3212 (2007/10/02)
A strategically novel approach to carbapenems has been developed.The pyrrolidine ring is first constructed, appended with the required side chains, and the β-lactam ring is then annealed.We have demonstrated the utility of the approach to the asymmetric s
