130518-34-2 Usage
Description
Methyl 6-hydroxy-2-methoxy-7,8-dihydroquinoline-5-carboxylate is a chemical compound with the molecular formula C13H13NO4. It is a derivative of quinoline, characterized by its unique structure that includes a methyl ester, hydroxy, methoxy, and carboxylate groups. Methyl 6-hydroxy-2-Methoxy-7,8-dihydroquinoline-5-carboxylate is recognized for its diverse biological activities and is commonly utilized in the synthesis of pharmaceuticals and agrochemicals.
Uses
Used in Pharmaceutical Industry:
Methyl 6-hydroxy-2-methoxy-7,8-dihydroquinoline-5-carboxylate is used as an intermediate in the synthesis of various biologically active compounds for the pharmaceutical industry. Its presence in the synthesis process is crucial due to its potential to contribute to the development of drugs with antitumor, antimalarial, and antibacterial properties.
Used in Agrochemical Industry:
In the agrochemical industry, Methyl 6-hydroxy-2-methoxy-7,8-dihydroquinoline-5-carboxylate is used as a key intermediate in the production of agrochemicals. Its role is pivotal in creating compounds that can effectively combat various agricultural pests and diseases, thereby enhancing crop protection and yield.
Used in Neurodegenerative Disease Research:
Methyl 6-hydroxy-2-methoxy-7,8-dihydroquinoline-5-carboxylate is also used as a research compound in the field of neurodegenerative diseases. Its potential application in this area is due to the compound's biological activities that may offer therapeutic benefits in the treatment and management of such conditions.
Overall, Methyl 6-hydroxy-2-methoxy-7,8-dihydroquinoline-5-carboxylate is a versatile chemical intermediate with significant applications across various industries, particularly in pharmaceutical and agrochemical development, as well as in research aimed at addressing complex health challenges.
Check Digit Verification of cas no
The CAS Registry Mumber 130518-34-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,0,5,1 and 8 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 130518-34:
(8*1)+(7*3)+(6*0)+(5*5)+(4*1)+(3*8)+(2*3)+(1*4)=92
92 % 10 = 2
So 130518-34-2 is a valid CAS Registry Number.
InChI:InChI=1S/C12H13NO4/c1-16-10-6-3-7-8(13-10)4-5-9(14)11(7)12(15)17-2/h3,6,11H,4-5H2,1-2H3
130518-34-2Relevant articles and documents
Development of a large-scale synthetic route to manufacture (-)-huperzine A
Tudhope, Stephen R.,Bellamy, Julie A.,Ball, Anthony,Rajasekar, Dewakar,Azadi-Ardakani, Manouchehr,Meera, Harihara Subramanian,Gnanadeepam, Jesudoss Mercy,Saiganesh, Ramanathan,Gibson, Frank,He, Linli,Behrens, Carl H.,Underiner, Gail,Marfurt, Judith,Favre, Nathalie
, p. 635 - 642 (2012/07/28)
A safe, practical and scalable process for manufacture of (-)-huperzine A has been developed and scaled up to manufacture several hundred grams of (-)-huperzine A with chemical and optical purity of >99%. The process consists of 11 chemical stages starting from commercially available materials with only nine isolation steps and no chromatography purification. This process provides a reliable and cost-effective source of synthetic (-)-huperzine A and its derivatives for pharmaceutical and nutraceutical markets.
Racemic huperzine A
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Page 16, (2010/11/29)
The present invention relates to racemic huperzine A, a pharmaceutical composition comprising huperzine A, its use as a medicament and for the manufacture of a medicament for the inhibition of the cholesterase enzymes in a mammal.
A formal synthesis of (+)-Huperzine A
Haudrechy, Arnaud,Chassaing, Christophe,Riche, Claude,Langlois, Yves
, p. 3181 - 3187 (2007/10/03)
A new formal stereoselective synthesis of (+)-Huperzine A (1) was achieved using as a key step a palladium mediated annulation between 2- methylene-1,3-propanediol diacetate and (1R,2S)-2-phenylcyclohexanol derived β-ketoester 2c. (C) 2000 Elsevier Science Ltd.
