130537-03-0Relevant academic research and scientific papers
Stereoselective synthesis of α-fluoroacrylonitriles: Via organocatalytic cyanation of gem -difluoroalkenes and TMSCN
Ma, Yu-Chuan,Zhang, Yang,Gu, Cheng-Zhi,Du, Guang-Fen,He, Lin
supporting information, p. 10985 - 10988 (2019/07/15)
An organocatalytic cyanation reaction of gem-difluoroalkenes was developed. Under the catalysis of 10 mol% DBU, gem-difluoroalkenes undergo a nucleophilic addition-β-elimination reaction with trimethylsilyl cyanide to provide α-fluoroacrylonitriles in 50-98% yields with excellent Z/E selectivity.
Stereoselective cyanation of β-bromo-β-fluorostyrenes using potassium cyanide and promoted by (CH3CN)4Cu+ BF4-
Eddarir, Said,Kajjout, Mohammed,Rolando, Christian
experimental part, p. 603 - 607 (2012/01/14)
A general method for the synthesis of α-fluorocinnamonitrile based on the stereoselective reaction between β-bromo-β-fluorostyrene and potassium cyanide, promoted by (CH3CN)4Cu+ BF4- in 1-methyl-2-pyr
Fluoro-Julia olefination as a mild, high-yielding route to α-fluoro acrylonitriles
Del Solar, Maria,Ghosh, Arun K.,Zajc, Barbara
experimental part, p. 8206 - 8211 (2009/04/11)
(Chemical Equation Presented) Synthesis of a novel, stable reagent (1,3-benzothiazol-2-ylsulfonyl)fluoroacetonitrile from readily synthesized ethyl α-(1,3-benzothiazol-2-ylsulfanyl)-α-fluoroacetate is reported. Aldehydes undergo condensations with (1,3-be
Preparation of Fluoralkenes from Fluoroacetonitrile
Patrick, Timothy B.,Nadji, Sourena
, p. 147 - 150 (2007/10/02)
A fluorocyanophosphate prepared from fluoroacetonitrile at low temperature reacts with aromatic aldehydes in a modified Wittig procedure to give fluorocyanoalkenes in moderate yield.
