130557-52-7Relevant academic research and scientific papers
Palladium-catalyzed cross-coupling reactions of brominated porphyrins with functionalized organomagnesium reagents: Direct preparation of functional-group-bearing free base porphyrins
Sugita, Noriaki,Tsuchiya, Ikumi,Takanami, Toshikatsu
, p. 483 - 511 (2017/04/10)
The direct preparation of free-base porphyrins possessing reactive functional groups such as esters, halides, amide, nitriles, and acetals is described. This method relies on a simple one-pot procedure that involves sequential palladium-catalyzed cross-coupling of brominated free-base porphyrins with functionalized aryl and alkenylmagnesium reagents, which are readily prepared by iodine-magnesium exchange of the corresponding organic iodides with the turbo Grignard reagent i-PrMgCl·LiCl, followed by demetallation of the resulting magnesium porphyrins under very mild conditions involving either a 1.2 M aqueous methanol solution of HCl or a 0.1 M methanol solution of citric acid at ambient temperature.
PORPHYRINS AND THEIR DERIVATIVES XII. SYNTHESIS OF ISOMERIC FORMYLPHENYLPORPHYRINS
Ishkov, Yu. V.,Zhilina, Z. I.
, p. 1156 - 1160 (2007/10/02)
Isomeric mono(o-, m-, p-cyanophenyl)triphenylporphyrins were synthesized by the condensation of a mixture of aldehydes (benzaldehyde-cyanobenzaldehyde, 4:1) with pyrrole in xylene in the presence of monochloroactic acid.Reduction of the para and meta isomers of the zinc complex of cyanoporphyrin with sodium triethoxyaluminohydride in THF and of the ortho isomer by aluminum hydride gives the corresponding formyl derivatives.
