130574-46-8Relevant academic research and scientific papers
Enantioselective Tail-to-Head Cyclizations Catalyzed by Dual-Hydrogen-Bond Donors
Kutateladze, Dennis A.,Strassfeld, Daniel A.,Jacobsen, Eric N.
, p. 6951 - 6956 (2020)
Chiral urea derivatives are shown to catalyze enantioselective tail-to-head cyclization reactions of neryl chloride analogues. Experimental data are consistent with a mechanism in which ?-participation by the nucleophilic olefin facilitates chloride ionization and thereby circumvents simple elimination pathways. Kinetic and computational studies support a cooperative mode of catalysis wherein two molecules of the urea catalyst engage the substrate and induce enantioselectivity through selective transition state stabilization.
Synthesis of 4-alkyl-4-(4-methoxyphenyl)cyclohex-2-en-1-ones and 5-alkyl-5-phenyl-1,3-cyclohexadienes from bis(tricarbonylchromium)-coordinated biphenyls
Rieke, Reuben D.,Schulte, Louis D.,Dawson, Bryan T.,Yang, Sheng Sbeng
, p. 8388 - 8398 (2007/10/02)
(η6:η6-Biphenyl)[Cr(CO)3] 2 and (η6η64,4'-dimethoxybiphenyl) [Cr(CO)3]2 were chemically reduced with lithium anthracenide or lithium naphthalenide in THF to generate s
