130584-48-4

Upstream product

• 71031-03-3 (2R)-1,2-epoxy-3-phenoxypropane 
• 107-18-6 allyl alcohol 
• 108-95-2 phenol 
• 20040-20-4 1-(allyloxy)-3-phenoxypropan-2-ol 
• 122-60-1 Phenyl glycidyl ether 

Downstream Products

• 130584-49-5 (R)-t-butyldimethyl<1-(phenoxymethyl)-2-(prop-2-enyloxy)ethoxy>silane 
• 130584-59-7 <1α,2β(R),4β>-methyl 3,3-dichloro-2-<2-(t-butyldimethylsilyloxy)-3-phenoxypropoxy>-4-hydroxycyclobutylheptanoate 
• 130584-59-7 <1α,2α(R),4α>-methyl 3,3-dichloro-2-<2-(t-butyldimethylsilyloxy)-3-phenoxypropoxy>-4-hydroxycyclobutylheptanoate 
• 130584-61-1 <1α,2α(R)>-methyl 2-<2-(t-butyldimethylsilyloxy)-3-phenoxypropoxy>-4-oxocyclobutylheptanoate 
• 130584-61-1 <1α,2β(R)>-methyl 2-<2-(t-butyldimethylsilyloxy)-3-phenoxypropoxy>-4-oxocyclobutylheptanoate 
• 130584-60-0 <1α,2α(R),4α>-methyl 2-<2-(t-butyldimethylsilyloxy)-3-phenoxypropoxy>-4-hydroxycyclobutylheptanoate 
• 130584-60-0 <1α,2β(R),4β>-methyl 2-<2-(t-butyldimethylsilyloxy)-3-phenoxypropoxy>-4-hydroxycyclobutylheptanoate 
• 130584-63-3 <2α,3α(R)>-methyl tetrahydro-3-(2-hydroxy-3-phenoxypropoxy)-5-oxo-2-furylheptanoate 
• 130584-63-3 <2α,3β(R)>-methyl tetrahydro-3-(2-hydroxy-3-phenoxypropoxy)-5-oxo-2-furylheptanoate 
• 130584-57-5 -methyl 9-<2-(t-butyldimethylsilyloxy)-3-phenoxypropoxy>non-8-enoate 
• 130584-62-2 <1α,2α(R)>-methyl 2-(2-hydroxy-3-phenoxypropoxy)-4-oxocyclobutylheptanoate 
• 130584-62-2 <1α,2β(R)>-methyl 2-(2-hydroxy-3-phenoxypropoxy)-4-oxocyclobutylheptanoate 
• 130584-52-0 <1α,3α(R),4β>-2,2-dichloro-3-<2-(t-butyldimethylsilyloxy)-3-phenoxypropoxy>-4-methylcyclobutanol 
• 130584-52-0 <1α,3α(R),4α>-2,2-dichloro-3-<2-(t-butyldimethylsilyloxy)-3-phenoxypropoxy>-4-methylcyclobutanol 

Relevant academic research and scientific papers

Asymmetric Transfer Hydrogenation of 1,3-Alkoxy/Aryloxy Propanones Using Tethered Arene/Ru(II)/TsDPEN Complexes

A series of propanones containing combinations of aryloxy and alkoxy substituents at the 1- and 3-positions were reduced to the alcohols via asymmetric transfer hydrogenation using a tethered Ru(II)/TsDPEN catalyst. The enantioselectivities of the reductions reveal a complex pattern of electronic and steric effects which, when used in a matched combination, can lead to the formation of products of up to 68% ee (84:16 er) from this highly challenging class of substrate.

The Synthesis of Novel Prostaglandin Analogues via Cycloaddition Reactions

The total synthesis of the cyclobutane prostaglandin analogues (4) and (5), and their subsequent conversion to the γ-lactones (6) and (7), γ-lactam (8) and cyclopentanone (9) is described.The cornerstone of the synthetic strategy is the intermolecular 2+