130584-63-3

Upstream product

• 108-95-2 phenol 
• 130584-59-7 <1α,2α(R),4α>-methyl 3,3-dichloro-2-<2-(t-butyldimethylsilyloxy)-3-phenoxypropoxy>-4-hydroxycyclobutylheptanoate 
• 130584-61-1 <1α,2α(R)>-methyl 2-<2-(t-butyldimethylsilyloxy)-3-phenoxypropoxy>-4-oxocyclobutylheptanoate 
• 130584-60-0 <1α,2α(R),4α>-methyl 2-<2-(t-butyldimethylsilyloxy)-3-phenoxypropoxy>-4-hydroxycyclobutylheptanoate 
• 130584-57-5 -methyl 9-<2-(t-butyldimethylsilyloxy)-3-phenoxypropoxy>non-8-enoate 
• 71031-03-3 (2R)-1,2-epoxy-3-phenoxypropane 
• 130584-56-4 -methyl 9-<2-(t-butyldimethylsilyloxy)-3-phenoxypropoxy>non-7-enoate 
• 130584-55-3 (R)-2-<2-(t-butyldimethylsilyloxy)-3-phenoxypropoxy>-ethanal 
• 130584-49-5 (R)-t-butyldimethyl<1-(phenoxymethyl)-2-(prop-2-enyloxy)ethoxy>silane 
• 130584-48-4 (R)-1-phenoxy-3-(prop-2-enyloxy)propan-2-ol 
• 130584-62-2 <1α,2α(R)>-methyl 2-(2-hydroxy-3-phenoxypropoxy)-4-oxocyclobutylheptanoate 
• 130584-59-7 <1α,2β(R),4β>-methyl 3,3-dichloro-2-<2-(t-butyldimethylsilyloxy)-3-phenoxypropoxy>-4-hydroxycyclobutylheptanoate 
• 130584-61-1 <1α,2β(R)>-methyl 2-<2-(t-butyldimethylsilyloxy)-3-phenoxypropoxy>-4-oxocyclobutylheptanoate 
• 130584-60-0 <1α,2β(R),4β>-methyl 2-<2-(t-butyldimethylsilyloxy)-3-phenoxypropoxy>-4-hydroxycyclobutylheptanoate 

Relevant academic research and scientific papers

The Synthesis of Novel Prostaglandin Analogues via Cycloaddition Reactions

The total synthesis of the cyclobutane prostaglandin analogues (4) and (5), and their subsequent conversion to the γ-lactones (6) and (7), γ-lactam (8) and cyclopentanone (9) is described.The cornerstone of the synthetic strategy is the intermolecular 2+