130599-96-1

Basic information

• Product Name: N-(4-Acetylphenyl)-2,2-dimethylpropanamide
• Synonyms: N-(4-Acetylphenyl)-2,2-dimethylpropanamide;N-(4-acetylphenyl)-2,2-dimethyl-propionamide;N-(4-ethanoylphenyl)-2,2-dimethyl-propanamide;ST5452029;ZINC05229432
• CAS NO: 130599-96-1
• Molecular Formula: C13H17NO2
• Molecular Weight: 219.27958
• Mol File: 130599-96-1.mol
• Article Data: 2

Chemical Properties

• Melting Point: 127.0-128.2 °C
• Boiling Point: 401.7±28.0 °C(Predicted)
• Appearance: /
• Density: 1.076±0.06 g/cm3(Predicted)
• PKA: 14.59±0.70(Predicted)
• CAS DataBase Reference: N-(4-Acetylphenyl)-2,2-dimethylpropanamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-Acetylphenyl)-2,2-dimethylpropanamide(130599-96-1)
• EPA Substance Registry System: N-(4-Acetylphenyl)-2,2-dimethylpropanamide(130599-96-1)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 130599-96-1(Hazardous Substances Data)

Upstream product

• 49647-20-3 4-acetylphenyl isocyanate 
• 75-98-9 Trimethylacetic acid 
• 3282-30-2 pivaloyl chloride 
• 99-92-3 p-aminobenzophenone 

Relevant articles and documents

General rhodium-catalyzed oxidative cross-coupling reactions between anilines: Synthesis of unsymmetrical 2,2′-diaminobiaryls

Described herein is a dual chelation-assisted RhCl3-catalyzed oxidative C-H/C-H cross-coupling reaction of aniline derivatives. The highlight of this methodology is the chemo- and regioselective cross-coupling between electronically similar substrates, which represents a highly challenging task in oxidative Ar-H/Ar-H cross-coupling reactions. Furthermore, this Cp?-free catalytic reaction tolerates a range of functional groups and requires only a low molar ratio of coupling partners. These features expedite the synthesis of unsymmetrical 2,2′-diaminobiaryls.