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1306-06-5

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1306-06-5 Usage

Description

Calcium hydroxyapatite has a unique structure in that it is conductive along the hydroxide channels. OH- ions lie at (1/4/,1/4,1/4) and (3/4/,3/4,3/4) on the c-axis and charge-carrying protons are responsible for the observed conductivities in M10(PO4)6(OH)2. The H+ migration between the electroattractive ion (O2) to give molecular H2O in matrix channels carries charge and the resulting conductivity. The unit cell consists of two triangular prismatic subcells forming a rhombic prism with vertical sides. There are two horizontal mirror planes at the OH levels of 1/4 and 3/4 of the c-axis. In addition, there is a center of inversion exactly in the center of each vertical face of each subcell.

Chemical Properties

Different sources of media describe the Chemical Properties of 1306-06-5 differently. You can refer to the following data:
1. Tricalcium phosphate is an odorless and tasteless powder that is stable in air. Tribasic calcium phosphate consists of a variable mixture of calcium phosphates having the approximate composition of 10CaO·3P2O5·H2O.
2. white powder

Occurrence

Occurs in nature as the minerals: oxydapatit, voelicherite, whitlockite.

Uses

Different sources of media describe the Uses of 1306-06-5 differently. You can refer to the following data:
1. Hydroxyapatite and tricalcium phosphate are bioactive ceramic materials and they find applications as bone grafts, fillers and coating material for metal implants.
2. Prosthetic aid (artificial bone and teeth).
3. In the 1970s, it was found that sintered calcium hydroxyapatite, (Ca10(PO4)6(OH)2 (abbreviated as CaHap), possessed excellent biocompatibility and nontoxicity with femur and mandible bones. Since then, CaHap has been used as a biomaterial for artificial teeth and bones and as a filler for cements and polymers. Today, bone fillers made of CaHap are widely used in the medical and dental fields. In the 1980s, it was found that sintered CaHap has a good compatibility with skin tissues. Hence, percutaneous devices based on CaHap have been developed and applications have included continuous ambulatory peritoneal dialysis and intravenous hyperalimentation systems, blood pressure measurement and blood access for nutrition. Recently, many researchers have studied the chemistry of apatites, particularly CaHap, and have found various applications, such as artificial teeth and bones, ion exchangers, adsorbents for chromatography to separate proteins and enzymes, catalysts, ionic conductors, temperature and gas sensors, etc.

Preparation

The technical product is also known as “bone ash.” Commercial preparation from phosphate rock.

Definition

The major constituent of bone and tooth mineral. It is finely divided, crystalline, nonstoichiometric material rich in surface ions (carbonate, magnesium, citrate), which are readily replaced by fluoride ion, thus affording protection to the teeth.

Brand name

Alveograf (Sterling Winthrop); Periograf (Sterling Winthrop).

General Description

Bone and tooth implant materials have been prepared from polycrystalline hydroxyapatite. The compressive, flexural, torsional and dynamic torsional strengths of polycrystalline hydroxyapatite were investigated. Electrophoretic deposition of hydroxyapatite on to flat titanium plate material has been studied.

Flammability and Explosibility

Notclassified

Pharmaceutical Applications

Modified hydroxylapatite, also frequently called hydroxyapatite and better known as bone mineral, makes up ~50% of our bones. Hydroxylapatite is a natural form of the mineral calcium apatite, whose formula is usually denoted as Ca10(PO4)6(OH)2. Modifications of hydroxylapatite can also be found in the teeth, and a chemically identical substance is often used as filler for replacement of bones, and so on. Nevertheless, despite similar or identical chemical compositions, the response of the body to these compounds can be quite different.

Check Digit Verification of cas no

The CAS Registry Mumber 1306-06-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,3,0 and 6 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1306-06:
(6*1)+(5*3)+(4*0)+(3*6)+(2*0)+(1*6)=45
45 % 10 = 5
So 1306-06-5 is a valid CAS Registry Number.
InChI:InChI=1/5Ca.H3O4P.H2O/c;;;;;1-5(2,3)4;/h;;;;;(H3,1,2,3,4);1H2/q5*+2;;/p-4

1306-06-5 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
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  • Sigma-Aldrich

  • (21223)  Hydroxyapatite  purum p.a., ≥90% (as Ca3(PO4)2, KT)

  • 1306-06-5

  • 21223-1KG

  • 1,599.39CNY

  • Detail
  • Aldrich

  • (900203)  Hydroxyapatite  powder, 10 μm, ≥100 m2/g

  • 1306-06-5

  • 900203-50G

  • 1,959.75CNY

  • Detail
  • Aldrich

  • (900204)  Hydroxyapatite  powder, 5 μm, surface area ≥100 m2/g

  • 1306-06-5

  • 900204-50G

  • 2,031.12CNY

  • Detail

1306-06-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name Hydroxyapatite

1.2 Other means of identification

Product number -
Other names Calcium phosphate hydroxide,Durapatite,Hydroxylapatite

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only. Agricultural chemicals (non-pesticidal),Fillers,Finishing agents,Intermediates,Process regulators
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1306-06-5 SDS

1306-06-5Upstream product

1306-06-5Downstream Products

1306-06-5Related news

Biosynthesis and characterization of Hydroxyapatite (cas 1306-06-5) and its composite (Hydroxyapatite (cas 1306-06-5)-gelatin-chitosan-fibrin-bone ash) for bone tissue engineering applications08/19/2019

Hydroxyapatite (HAp) is a bioactive and biocompatible material possessing osteoconductive properties used widely in the biomedical sector. In the present study, synthesis of hydroxyapatite (HAp) using a Klebsiella pneumoniae SM24 (phosphate solubilizing bacteria) isolated from the slaughterhouse...detailed

Painting method for Hydroxyapatite (cas 1306-06-5) coating on titanium substrate08/18/2019

Coating on prostheses and implantable devices is one of the ways to increase the osseointegration of these products. However, plasma spray techniques, that are normally used, present high complexity and high cost. In this work, a new methodology for coating with nanometric hydroxyapatite is pres...detailed

Qualitative analysis on crystal growth of synthetic Hydroxyapatite (cas 1306-06-5) influenced by fluoride concentration08/16/2019

ObjectiveThis study was designed to analyze the crystal growth of synthetic hydroxyapatite (HA) particles in pH 7.0 supersaturated solutions with different fluoride concentrations by FE-SEM, FE-TEM, X-ray diffraction (XRD), and FTIR.detailed

Characterization of Hydroxyapatite (cas 1306-06-5) from eggshell waste and polycaprolactone (PCL) composite for scaffold material08/14/2019

Hydroxyapatite was successfully synthesized from eggshell waste. In addition, 10, 20, and 30 wt% hydroxyapatite/polycaprolactone (PCL) composites were prepared. The composites were prepared by dispersing hydroxyapatite particles in PCL. The structural properties of the composites were characteri...detailed

Impact of morphology-influencing factors in lecithin-based Hydroxyapatite (cas 1306-06-5) precipitation08/12/2019

Lecithin-based hydroxyapatite (HAp-LE) precipitation allows synthesis of biocompatible nanosized particles. In our previous paper regarding this process, we concluded that the concentration of lecithin gives control over the size and morphology of such particles. In this paper, a special emphasi...detailed

Effects of MoOx modification on photocatalytic activity of Hydroxyapatite (cas 1306-06-5) and Ti-doped Hydroxyapatite (cas 1306-06-5)08/10/2019

Titanium-doped hydroxyapatite (Ti-HAp, (Ca10-2x, Tix, □x) (PO4)6(OH)2, □: defect in Ca site) and hydroxyapatite (HAp, Ca10(PO4)6(OH)2) powders were modified with an ethanol solution of molybdenyl acetylacetonate (MoO2(C5H8O2)2) using chemisorption calcination cycle (CCC) technique, which provi...detailed

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