Biosynthesis and characterization of Hydroxyapatite (cas 1306-06-5) and its composite (Hydroxyapatite (cas 1306-06-5)-gelatin-chitosan-fibrin-bone ash) for bone tissue engineering applications
-
Add time:08/19/2019 Source:sciencedirect.com
Hydroxyapatite (cas 1306-06-5) (HAp) is a bioactive and biocompatible material possessing osteoconductive properties used widely in the biomedical sector. In the present study, synthesis of hydroxyapatite (HAp) using a Klebsiella pneumoniae SM24 (phosphate solubilizing bacteria) isolated from the slaughterhouse. HAp synthesized using biological source showed efficient and positive enzymatic activity in the National Botanical Research Institute Phosphate Medium (NBRIP). Characterization of HAp using FTIR revealed the presence of phosphate group hydroxyapatite and XRD spectra showed polycrystalline nature. The morphological characterization of HAp using FESEM revealed the mesoporous structure and EDX spectrum indicated presence of Ca and P as the major components. In addition, a new bone composite was prepared using the synthesized HAp, Gelatine (G), Chitosan (C), Fibrin (F) and Bone ash (HApGCF) using Simulated Body Fluid (SBF) solution. The confirmation of chemical and structural characteristics of HApGCF bone composite was achieved using FTIR, XRD and SEM analyses. The HApGCF bone composite was tested over osteoblast MG-63 cells showing effective biocompatibility and osteoblast attachment on the composite surface. Therefore, the present report proposes the in vitro application of HApGCF bone composite as a replacement for major bone damage and injury in a biocompatible and non-toxic way.
We also recommend Trading Suppliers and Manufacturers of Hydroxyapatite (cas 1306-06-5). Pls Click Website Link as below: cas 1306-06-5 suppliers
Prev:Painting method for Hydroxyapatite (cas 1306-06-5) coating on titanium substrate
Next:The crystallization and properties of sputter deposited lithium Niobite (cas 1306-08-7)) - 【Back】【Close 】【Print】【Add to favorite 】
- Related Information
- Painting method for Hydroxyapatite (cas 1306-06-5) coating on titanium substrate08/18/2019
- Design and fabrication of pyrolytic carbon-SiC-fluoridated Hydroxyapatite (cas 1306-06-5)-Hydroxyapatite (cas 1306-06-5) multilayered coating on carbon fibers08/17/2019
- Qualitative analysis on crystal growth of synthetic Hydroxyapatite (cas 1306-06-5) influenced by fluoride concentration08/16/2019
- Effect of fluorine substitution on sintering behaviour, mechanical and bioactivity of Hydroxyapatite (cas 1306-06-5)08/15/2019
- Characterization of Hydroxyapatite (cas 1306-06-5) from eggshell waste and polycaprolactone (PCL) composite for scaffold material08/14/2019
- Synthesis and properties of alumina-Hydroxyapatite (cas 1306-06-5) composites from natural phosphate for phenol removal from water08/13/2019
- Impact of morphology-influencing factors in lecithin-based Hydroxyapatite (cas 1306-06-5) precipitation08/12/2019
- Microwave assisted synthesis of biomorphic Hydroxyapatite (cas 1306-06-5)08/11/2019
- Effects of MoOx modification on photocatalytic activity of Hydroxyapatite (cas 1306-06-5) and Ti-doped Hydroxyapatite (cas 1306-06-5)08/10/2019