130660-14-9Relevant academic research and scientific papers
CONJUGATE REDUCTION OF POLYFUNCTIONAL α,β-UNSATURATED CARBONYL COMPOUNDS USING 6. COMPATIBILITY WITH HALOGEN, SULFONATE, AND SULFUR SUBSTITUENTS
Koenig, Thomas M.,Daeuble, John F.,Brestensky, Donna M.,Stryker, Jeffrey M.
, p. 3237 - 3240 (2007/10/02)
In contrast to organocuprate conjugate addition and standard methods for conjugate reduction, use of the stable copper(I) hydride cluster, 6, allows chemoselective conjugate reduction of α,β-unsaturated carbonyl compounds substituted at the γ-position with leaving groups.In addition, the compatibility of the conjugate reduction with organic halides and sulfonate groups is demonstrated.
