1306760-85-9

Basic information

• Product Name: Benzonitrile, 5-[3-[(1S)-2,3-dihydro-1-[(2-hydroxyethyl)aMino]-1H-inden-4-yl]-1,2,4-oxadiazol-5-yl]-2-(1-Methylethoxy)- (HCl salt)
• Synonyms: Benzonitrile, 5-[3-[(1S)-2,3-dihydro-1-[(2-hydroxyethyl)aMino]-1H-inden-4-yl]-1,2,4-oxadiazol-5-yl]-2-(1-Methylethoxy)- (HCl salt);R-Ozanimod Hydrochloride;Ozanimod.hcl;5-[3-[(1R)-1-(2-hydroxyethylamino)-2,3-dihydro-1H-inden-4-yl]-1,2,4-oxadiazol-5-yl]-2-propan-2-yloxybenzonitrile:hydrochloride
• CAS NO: 1306760-85-9
• Molecular Formula: C23H25ClN4O3
• Molecular Weight: 440.9226
• Mol File: 1306760-85-9.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzonitrile, 5-[3-[(1S)-2,3-dihydro-1-[(2-hydroxyethyl)aMino]-1H-inden-4-yl]-1,2,4-oxadiazol-5-yl]-2-(1-Methylethoxy)- (HCl salt)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzonitrile, 5-[3-[(1S)-2,3-dihydro-1-[(2-hydroxyethyl)aMino]-1H-inden-4-yl]-1,2,4-oxadiazol-5-yl]-2-(1-Methylethoxy)- (HCl salt)(1306760-85-9)
• EPA Substance Registry System: Benzonitrile, 5-[3-[(1S)-2,3-dihydro-1-[(2-hydroxyethyl)aMino]-1H-inden-4-yl]-1,2,4-oxadiazol-5-yl]-2-(1-Methylethoxy)- (HCl salt)(1306760-85-9)

Safety Data

• Hazardous Substances Data: 1306760-85-9(Hazardous Substances Data)

Usage

General Description

Benzonitrile, 5-[3-[(1S)-2,3-dihydro-1-[(2-hydroxyethyl)amino]-1H-inden-4-yl]-1,2,4-oxadiazol-5-yl]-2-(1-methylethoxy)- (HCl salt) is a chemical compound that is used in pharmaceutical research and development. It is a HCl salt form of a compound that contains a benzene ring, a nitrile group, an oxadiazole ring, and an indene ring. This chemical may have potential applications in the treatment of various medical conditions, and its structure and properties make it a valuable target for drug discovery. Understanding the properties and potential uses of this compound is important for furthering our knowledge of its potential medicinal applications.

Upstream product

• 258273-31-3 3-cyano-4-isopropoxybenzoic acid 
• 1306760-86-0 5-(3-{(1S)-1-[(2-hydroxyethyl)amino]-2,3-dihydro-1H-inden-4-yl}-1,2,4-oxadiazol-5-yl)-2-[(propan-2-yl)oxy]benzonitrile 
• 1306763-24-5 (R)-1-hydroxy-2,3-dihydro-1H-indene-4-carbonitrile 
• 1213099-69-4 (S)-(1-amino-2,3-dihydro-1H-indene-1-yl)-4-carbonitrile 
• 1306763-62-1 (S)-tert-butyl 2-(tert-butyldimethylsilyloxy)ethyl-(4-(N-hydroxycarbamimidoyl)-2,3-dihydro-1H-inden-1-yl)carbamate 

Relevant articles and documents

IMPROVED PROCESS FOR PREPARING OZANIMOD

The presented invention relates to a process for preparation of compound of formula (1) or a salt thereof (i.e.) ozanimod : (1). The invention also relates to intermediates used in the process.

PROCESS FOR THE PREPARATION OF SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONIST

Industrially viable and advantageous processes for the preparation of Ozanimod are described. The invention also discloses the intermediates obtained in the process.

COMPOUNDS AND METHODS FOR TREATING LUPUS

Methods for treatment of systemic lupus erythematosus (SLE" or "Lupus") by administration of a modulator of sphingosine-1-phosphate receptor subtype 1 (S1P1), as well as compositions and methods related to the same, wherein such S1P1 modulators have the f