1306763-62-1

Basic information

• Product Name: (S)-tert-butyl 2-(tert-butyldimethylsilyloxy)ethyl-(4-(N-hydroxycarbamimidoyl)-2,3-dihydro-1H-inden-1-yl)carbamate
• CAS NO: 1306763-62-1
• Molecular Weight: 449.666
• Mol File: 1306763-62-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (S)-tert-butyl 2-(tert-butyldimethylsilyloxy)ethyl-(4-(N-hydroxycarbamimidoyl)-2,3-dihydro-1H-inden-1-yl)carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-tert-butyl 2-(tert-butyldimethylsilyloxy)ethyl-(4-(N-hydroxycarbamimidoyl)-2,3-dihydro-1H-inden-1-yl)carbamate(1306763-62-1)
• EPA Substance Registry System: (S)-tert-butyl 2-(tert-butyldimethylsilyloxy)ethyl-(4-(N-hydroxycarbamimidoyl)-2,3-dihydro-1H-inden-1-yl)carbamate(1306763-62-1)

Safety Data

• Hazardous Substances Data: 1306763-62-1(Hazardous Substances Data)

Usage

General Description

(S)-tert-butyl 2-(tert-butyldimethylsilyloxy)ethyl-(4-(N-hydroxycarbamimidoyl)-2,3-dihydro-1H-inden-1-yl)carbamate is a complex chemical compound with a long and specific name. It is a carbamate derivative with a tert-butyl group and a tert-butyldimethylsilyloxy group attached to the ethyl chain. Additionally, it contains a hydroxycarbamimidoyl group and an indenyl group. (S)-tert-butyl 2-(tert-butyldimethylsilyloxy)ethyl-(4-(N-hydroxycarbamimidoyl)-2,3-dihydro-1H-inden-1-yl)carbamate is likely to be used in organic synthesis, potentially as a reagent or building block for creating more complex organic molecules. Due to its complex structure, it may have specific applications in medicinal chemistry or materials science. However, further research and analysis would be required to fully understand the potential uses and properties of this compound.

Upstream product

• 60899-34-5 4-cyano-2,3-dihydro-1H-inden-1-one 
• 1306763-31-4 tert-butyl N-[(1S)-4-cyano-2,3-dihydro-1H-inden-1-yl]carbamate 
• 1306763-57-4 (S)-1-amino-2,3-dihydro-1H-indene-4-carbonitrile hydrochloride 
• 24424-99-5 di-tert-butyl dicarbonate 
• 86864-60-0 2-(tert-butyldimethylsilyloxy)ethyl bromide 
• 1306763-41-6 (R)-tert-butyl 2-(tert-butyldimethylsilyloxy)ethyl(4-cyano-2,3-dihydro-1H-inden-1-yl)carbamate 
• 1306763-30-3 (R)-tert-butyl 4-cyano-2,3-dihydro-1H-inden-1-ylcarbamate 
• 1306763-29-0 (R)-(1-amino-2,3-dihydro-1H-indene-1-yl)-4-carbonitrile hydrochloride 
• 1306763-28-9 (R)-N-((R)-4-cyano-2,3-dihydro-1H-inden-1-yl)-2-methylpropane-2-sulfinamide 
• 1306763-27-8 (R)-N-(4-cyano-2,3-dihydro-1H-indene-1-ylidene)-2-methylpropane-2-sulfinamide 
• 15115-60-3 4-bromo-2,3-dihydroinden-1-one 

Downstream Products

• 1307231-27-1 (R)-tert-butyl (2-((tert-butyldimethylsilyl)oxy)ethyl)(4-(N-((4-phenyl-5-(trifluoromethyl)thiophene-2-carbonyl)oxy)carbamimidoyl)-2,3-dihydro-1H-inden-1-yl)carbamate 
• 1307231-07-7 (R)-tert-butyl 2-(tert-butyldimethylsilyloxy)ethyl(4-(5-(4-phenyl-5-(trifluoromethyl)thiophen-2-yl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl)carbamate 
• 1306760-86-0 (R)-5-(3-(1-(2-hydroxyethylamino)-2,3-dihydro-1H-inden-4-yl)-1,2,4-oxadiazol-5-yl)-2-isopropoxybenzonitrile 
• 1306760-86-0 5-(3-{(1S)-1-[(2-hydroxyethyl)amino]-2,3-dihydro-1H-inden-4-yl}-1,2,4-oxadiazol-5-yl)-2-[(propan-2-yl)oxy]benzonitrile 

Relevant articles and documents

IMPROVED PROCESS FOR THE PREPARATION OF OZANIMOD Α-AMINO COMPOUND

The present invention relates to an improved process for the preparation of optically chiral amino compound. The present invention particularly relates to the improved process for the preparation of (S)-1-amino-2,3-dihydro-1H-indene-4-carbonitrile, an important intermediate for the synthesis of ozanimod. The present invention more particularly relates to preparation of (S)-1-amino-2,3-dihydro-1H-indene-4- carbonitrile using 4-cyano-1-indanone and α-methylbenzylamine derivatives as starting materials. The present invention specifically relates to preparation of (S)-1- amino-2,3-dihydro-1H-indene-4-carbonitrile comprising diastereoselective chiral amine synthesis by protection with chiral auxiliary ?-methyl benzylamine derivatives followed by reduction and debenzylation.

SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS AND METHODS OF CHIRAL SYNTHESIS

Compounds that selectively modulate the sphingosine 1 phosphate receptor are provided including compounds which modulate subtype 1 of the S1P receptor. Methods of chiral synthesis of such compounds is provided. Uses, methods of treatment or prevention and methods of preparing inventive compositions including inventive compounds are provided in connection with the treatment or prevention of diseases, malconditions, and disorders for which modulation of the sphingosine 1 phosphate receptor is medically indicated.