130680-89-6

Upstream product

• 50919-06-7 2-(2-fluorophenyl)ethanol 
• 124-63-0 methanesulfonyl chloride 
• 451-82-1 (2-fluorophenyl)acetic acid 

Downstream Products

• 178685-13-7 2-fluoro-1-(2-iodoethyl)benzene 
• 694-87-1 benzocyclobutene 
• 1708-59-4 Methyl Bicyclo<4.2.0>octa-1,3,5-triene-2-carboxylate 
• 877149-83-2 3-(2-fluorophenyl)propanenitrile 
• 1055321-63-5 dimethyl 2-[2-(2-fluorophenyl)ethyl]malonate 
• 1643-26-1 3-(2-fluorophenyl)propionic acid 
• 76727-24-7 3-(2-fluorophenyl)propan-1-ol 
• 39856-89-8 ethyl 3-(2-fluorophenyl)propionate 

Relevant academic research and scientific papers

6,11-dihydro-5H-benzo[d]imidazo[1,2-a]azepines derivatives as histamine H4 receptor ligands

The present patent application concerns new ligands of the H4-receptor, their process of preparation and their therapeutic use.

SUBSTITUTED AROMATIC CARBOXAMIDE AND UREA DERIVATIVES AS VANILLOID RECEPTOR LIGANDS

The invention relates to substituted aromatic carboxamide and urea derivatives, to processes for the preparation thereof, to pharmaceutical compositions containing these compounds and also to the use of these compounds for preparing pharmaceutical compositions (formula (I)).

BENZIMIDAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF

Provided is an ORL-1 receptor agonist having improved bioavailability based on superior metabolic stability and strong and high selectivity, as compared to conventional compounds. A compound represented by the formula (I) wherein each symbol is as defined

THERAPEUTIC FLUOROETHYLCYANO GUANIDINES

Disclosed herein is compound having a formula as described herein. Therapeutic methods, compositions, and medicaments related thereto are also disclosed.

NEW OXABISPIDINE COMPOUNDS FOR THE TREATMENT OF CARDIAC ARRHYTHMIAS

There is provided compounds of formula I, [Chemical formula should be inserted here. Please see paper copy] wherein R1 to R4 , R41 to R46 and Z have meanings given in the description, which are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias

NOVEL OXABISPIDINE COMPOUNDS AND THEIR USE IN THE TREATMENT OF CARDIAC ARRHYTHMIAS

There is provided compounds of formula (I), wherein R1, R2, R3, R4, R 41 to R46, A, B and G have meanings given in the description, which are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias.

Cyclization of benzyne-tethered alkyllithiums: Preparation of 3-substituted benzocyclobutenes and 5-substituted tetralins

A five-step, one-pot preparation of isomerically pure 3-substituted benzocyclobutenes or 5-substituted tetralins in 20-40% yield from the appropriate α-(2-fluorophenyl)-ω-iodoalkane, involving generation and subsequent 4-or 6-exo cyclization of a benzyne-tethered alkyllithium, is described.