1306830-06-7

Basic information

• Product Name: C₂₁H₂₈N₆O
• CAS NO: 1306830-06-7
• Molecular Weight: 380.493
• Mol File: 1306830-06-7.mol

Chemical Properties

• CAS DataBase Reference: C₂₁H₂₈N₆O(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₁H₂₈N₆O(1306830-06-7)
• EPA Substance Registry System: C₂₁H₂₈N₆O(1306830-06-7)

Safety Data

• Hazardous Substances Data: 1306830-06-7(Hazardous Substances Data)

Upstream product

• 100047-42-5 6-(methylsulfanyl)-1H,2H,3H-pyrazolo[3,4-d]pyrimidin-3-one 
• 5909-24-0 4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester 
• 5720-07-0 4-methoxyphenylboronic acid 
• 1306829-96-8 3-bromo-N-propyl-1H-pyrazolo[3,4-d]pyrimidin-6-amine 
• 1306829-95-7 3-bromo-6-(methylsulfanyl)-1H-pyrazolo[3,4-d]pyrimidine 

Relevant articles and documents

PYRAZOLOPYRIMIDINE COMPOUNDS FOR THE TREATMENT OF CANCER

Compound of Formula (I): are described, along with pharmaceutically acceptable salts thereof, compositions containing the same, and methods of use thereof in the treatment of cancer.

Microwave-assisted, divergent solution-phase synthesis of 1,3,6-trisubstituted pyrazolo[3,4- d ]pyrimidines

A concise and highly divergent synthetic route has been developed to rapidly access 1,3,6-trisubstituted pyrazolopyrimidines. The synthesis features a microwave assisted one-pot N1-alkylation/Suzuki-Miyaura reaction as the key step. The sequence of the synthetic scheme can be varied to selectively modify the N1, C3, or C6 position at a late synthetic stage, thereby providing a highly efficient approach to explore the structure-activity relationships of pyrazolopyrimidine derivatives. The scope of these reactions has also been explored.