1307255-37-3

Usage

Uses

Used in Pharmaceutical Synthesis:
1-(2-chloro-3-methoxyphenyl)ethanone is used as an intermediate in the synthesis of pharmaceuticals for its versatile chemical properties, contributing to the development of various medicinal compounds.
Used in Flavoring Agents:
In the food industry, 1-(2-chloro-3-methoxyphenyl)ethanone is used as a flavoring agent, adding unique taste and aroma to different products.
Used in Organic Compounds Synthesis:
This chemical is also utilized as an intermediate in the synthesis of other organic compounds, showcasing its importance in the chemical industry and the manufacturing of a wide range of products.

Upstream product

• 586-37-8 1-(3-Methoxyphenyl)ethanone 
• 1307255-36-2 1-(2-chloro-3-methoxyphenyl)ethanol 
• 54881-49-1 2-chloro-3-methoxy benzaldehyde 

Downstream Products

• 69240-96-6 1-(2-chloro-3-hydroxyphenyl)ethanone 
• 1307255-38-4 tert-butyl (3-endo)-3-(3-acetyl-2-chlorophenoxy)-8-azabicyclo[3.2.1]octane-8-carboxylate 

Relevant academic research and scientific papers

SMYD INHIBITORS

The present disclosure provides carboxamides and sulfonamides having Formula (I): and the pharmaceutically acceptable salts and solvates thereof, wherein A, Y, B, X, and Z are defined as set forth in the specification. The present disclosure is also directed to the use of compounds of Formula (I) to treat a disorder responsive to the blockade of SMYD proteins such as SMYD3 or SMYD2. Compounds of the present disclosure are especially useful for treating cancer.

Room temperature C(sp2)-H oxidative chlorination: Via photoredox catalysis

Photoredox catalysis has been developed to achieve oxidative C-H chlorination of aromatic compounds using NaCl as the chlorine source and Na2S2O8 as the oxidant. The reactions occur at room temperature and exhibit exclusive selectivity for C(sp2)-H bonds over C(sp3)-H bonds. The method has been used for the chlorination of a diverse set of substrates, including the expedited synthesis of key intermediates to bioactive compounds and a drug.

8-AZABICYCLO[3.2.1]OCTANE-8-CARBOXAMIDE DERIVATIVE

Disclosed is a compound represented by formula (1) or a pharmacologically acceptable salt thereof (In the formula, A represents a group that is represented by formula (A-1); R1a and R1b may be the same or different and each independently represents a C1-6 alkyl group which may be substituted by one to three halogen atoms; m and n each independently represents an integer of 0-5; X1 represents a hydroxyl group or an aminocarbonyl group; Z1 represents a single bond or the like; and R2 represents an optionally substituted C1-6 alkyl group, an optionally substituted C6-10 aryl group or the like.)