69240-96-6

Basic information

• Product Name: Ethanone, 1-(2-chloro-3-hydroxyphenyl)-
• Synonyms: 2-chloro-3-hydroxyacetophenone;2-chloro-3-hydroxy-acetophenone;1-(2-chloro-3-hydroxyphenyl)ethanone
• CAS NO: 69240-96-6
• Molecular Formula: C8H7ClO2
• Molecular Weight: 170.595
• Mol File: 69240-96-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-(2-chloro-3-hydroxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-(2-chloro-3-hydroxyphenyl)-(69240-96-6)
• EPA Substance Registry System: Ethanone, 1-(2-chloro-3-hydroxyphenyl)-(69240-96-6)

Safety Data

• Hazardous Substances Data: 69240-96-6(Hazardous Substances Data)

Usage

General Description

Ethanone, 1-(2-chloro-3-hydroxyphenyl)- is a chemical compound that is also known as 3-Hydroxy-2′-chloroacetophenone. It is a white crystalline solid with a molecular formula C8H7ClO2 and a molecular weight of 170.59 g/mol. Ethanone, 1-(2-chloro-3-hydroxyphenyl)- is commonly used in the pharmaceutical industry as an intermediate in the synthesis of various pharmaceutical compounds. It is also used in the production of organic chemicals and as a reagent in chemical reactions. Ethanone, 1-(2-chloro-3-hydroxyphenyl)- may have other applications in industries such as cosmetics and agriculture, due to its specific chemical properties.

Upstream product

• 121-71-1 3-Hydroxyacetophenone 
• 1307255-37-3 1-(2-chloro-3-methoxyphenyl)ethanone 
• 1307255-36-2 1-(2-chloro-3-methoxyphenyl)ethanol 
• 54881-49-1 2-chloro-3-methoxy benzaldehyde 

Downstream Products

• 959999-74-7 1,1-dimethylethyl 4-[(3-acetyl-2-chlorophenyl)oxy]-1-piperidinecarboxylate 
• 929280-82-0 1-(2-chloro-3-{[(1,1-dimethylethyl)(dimethyl)silyl]oxy}phenyl)ethanone 
• 1307255-38-4 tert-butyl (3-endo)-3-(3-acetyl-2-chlorophenoxy)-8-azabicyclo[3.2.1]octane-8-carboxylate 

Relevant articles and documents

Ammonium Salt-Catalyzed Highly Practical Ortho-Selective Monohalogenation and Phenylselenation of Phenols: Scope and Applications

An ortho-selective ammonium chloride salt-catalyzed direct C-H monohalogenation of phenols and 1,1′-bi-2-naphthol (BINOL) with 1,3-dichloro-5,5-dimethylhydantoin (DCDMH) as the chlorinating agent has been developed. The catalyst loading was low (down to 0.01 mol %) and the reaction conditions were very mild. A wide range of substrates including BINOLs were compatible with this catalytic protocol. Chlorinated BINOLs are useful synthons for the synthesis of a wide range of unsymmetrical 3-aryl BINOLs that are not easily accessible. In addition, the same catalytic system can facilitate the ortho-selective selenylation of phenols.

8-AZABICYCLO[3.2.1]OCTANE-8-CARBOXAMIDE DERIVATIVE

Disclosed is a compound represented by formula (1) or a pharmacologically acceptable salt thereof (In the formula, A represents a group that is represented by formula (A-1); R1a and R1b may be the same or different and each independently represents a C1-6 alkyl group which may be substituted by one to three halogen atoms; m and n each independently represents an integer of 0-5; X1 represents a hydroxyl group or an aminocarbonyl group; Z1 represents a single bond or the like; and R2 represents an optionally substituted C1-6 alkyl group, an optionally substituted C6-10 aryl group or the like.)