130726-68-0 Usage
General Description
Neticonazole is a broad-spectrum antifungal agent that belongs to the imidazole class of drugs. It works by inhibiting the synthesis of ergosterol, a key component of fungal cell membranes, leading to disruption of the fungal cell wall and ultimately cell death. This mechanism of action makes neticonazole effective against a wide range of fungal infections, including those caused by dermatophytes and yeasts. It is often used in the treatment of skin infections such as athlete's foot, ringworm, and candidiasis. Neticonazole is available in topical formulations, such as creams and ointments, and is generally well-tolerated with minimal systemic side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 130726-68-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,0,7,2 and 6 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 130726-68:
(8*1)+(7*3)+(6*0)+(5*7)+(4*2)+(3*6)+(2*6)+(1*8)=110
110 % 10 = 0
So 130726-68-0 is a valid CAS Registry Number.
InChI:InChI=1/C17H22N2OS/c1-3-4-7-12-20-17-9-6-5-8-15(17)16(13-21-2)19-11-10-18-14-19/h5-6,8-11,13-14H,3-4,7,12H2,1-2H3/b16-13+
130726-68-0Relevant articles and documents
Synthesis and antifungal activities of a series of (1,2-disubstituted vinyl)imidazoles
Ogawa,Matsuda,Eto,Asaoka,Kuraishi,Iwasa,Nakashima,Yamaguchi
, p. 2301 - 2307 (2007/10/02)
A series of vinylimidazoles containing a hetero atom such as sulfur or oxygen at a β-position of the vinyl group was prepared and the antifungal activities were tested. It was found that sulfur-substituted derivatives such as (E)-1-[2-(methylthio)-1-[2-(p
