138206-46-9

Usage

Uses

Used in Pharmaceutical Industry:
Phenol, 2-[1-(1H-imidazol-1-yl)-2-(methylthio)ethenyl]is used as a potential candidate in drug design and development for its ability to interact with various proteins and enzymes, which is crucial in the creation of new therapeutic agents.
Used in Cancer Treatment Research:
In the field of oncology, Phenol, 2-[1-(1H-imidazol-1-yl)-2-(methylthio)ethenyl]- is being explored for its potential role in cancer treatment, given its capacity to bind with biological targets that may be implicated in cancer progression and cell growth.
Used in Anti-Inflammatory Drug Development:
Phenol, 2-[1-(1H-imidazol-1-yl)-2-(methylthio)ethenyl]is also considered for the development of anti-inflammatory drugs, where its interaction with specific biological targets could help in managing inflammation and related conditions.
Used in Biological Research:
Phenol, 2-[1-(1H-imidazol-1-yl)-2-(methylthio)ethenyl]serves as a valuable tool in biological research, aiding scientists in understanding the mechanisms of action and potential therapeutic effects of similar chemical structures on various biological systems.

Upstream product

• 288-32-4 1H-imidazole 
• 56986-82-4 α,α-dibromo-o-hydroxyacetophenone 
• 69-72-7 salicylic acid 
• 24276-77-5 bromomethyl methyl sulfide 
• 80282-49-1 1-(1-(2-hydroxyphenyl)-2-methanone)-1H-imidazole 
• 2491-36-3 2-(2-bromoacetyl)hydroxybenzene 

Downstream Products

• 138206-56-1 1-[(E)-1-(2-Ethoxy-phenyl)-2-methylsulfanyl-vinyl]-1H-imidazole 
• 138206-60-7 1-[(E)-1-(2-Heptyloxy-phenyl)-2-methylsulfanyl-vinyl]-1H-imidazole 
• 130773-02-3 (E)-1-[2-methylthio-1-[2-(pentyloxy)phenyl]ethenyl]-1H-imidazole hydrochloride 
• 138206-85-6 1-[(Z)-1-(2-Hexyloxy-phenyl)-2-methylsulfanyl-vinyl]-1H-imidazole 
• 138206-84-5 1-[(Z)-2-Methylsulfanyl-1-(2-pentyloxy-phenyl)-vinyl]-1H-imidazole 
• 138206-83-4 1-[(Z)-1-(2-Butoxy-phenyl)-2-methylsulfanyl-vinyl]-1H-imidazole 
• 138206-63-0 1-{(E)-1-[2-(2,4-Dichloro-benzyloxy)-phenyl]-2-methylsulfanyl-vinyl}-1H-imidazole 
• 138206-50-5 (Z)-1-<1-(2-Hydroxyphenyl)-2-(methylthio)ethenyl>-1H-imidazole 
• 138206-57-2 1-[(E)-2-Methylsulfanyl-1-(2-propoxy-phenyl)-vinyl]-1H-imidazole 
• 138206-62-9 1-[(E)-1-(2-Benzyloxy-phenyl)-2-methylsulfanyl-vinyl]-1H-imidazole 
• 138206-61-8 1-[(E)-2-Methylsulfanyl-1-(2-octyloxy-phenyl)-vinyl]-1H-imidazole 
• 138206-59-4 (E)-1-<1-<2-(Hexyloxy)phenyl>-2-(methylthio)ethenyl>-1H-imidazole 
• 130726-68-0 (E)-1-<2-(Methylthio)-1-<2-(pentyloxy)phenyl>ethenyl>-1H-imidazole 
• 138206-55-0 1-[(E)-1-(2-Methoxy-phenyl)-2-methylsulfanyl-vinyl]-1H-imidazole 

Relevant academic research and scientific papers

Neticonazole hydrochloride preparation method

The invention discloses a neticonazole hydrochloride preparation method, which comprises: carrying out an acylation reaction on imidazole and o-hydroxybenzoic acid, carrying out a wittig reaction on the product of the acylation reaction and 1-halogenated dimethyl sulfide, carrying out a reaction on the product of the wittig reaction and 1-halogenated pentane in an inorganic alkali, and salifying the product of the reaction and hydrochloric acid to obtain the neticonazole hydrochloride. According to the present invention, the method can avoid the use of the methanethiol and thionyl chloride, has characteristics of environmental protection, mild reaction condition, simple operation, simple post-treatment and high product purity, and is suitable for industrial production.

Synthesis and antifungal activities of a series of (1,2-disubstituted vinyl)imidazoles

A series of vinylimidazoles containing a hetero atom such as sulfur or oxygen at a β-position of the vinyl group was prepared and the antifungal activities were tested. It was found that sulfur-substituted derivatives such as (E)-1-[2-(methylthio)-1-[2-(p