138206-46-9

Basic information

• Product Name: Phenol, 2-[1-(1H-imidazol-1-yl)-2-(methylthio)ethenyl]-
• Synonyms: Phenol, 2-[1-(1H-imidazol-1-yl)-2-(methylthio)ethenyl]-
• CAS NO: 138206-46-9
• Molecular Formula: C₁₂H₁₂N₂OS
• Molecular Weight: 232.30148
• Mol File: 138206-46-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 438.4±55.0 °C(Predicted)
• Appearance: /
• Density: 1.19±0.1 g/cm3(Predicted)
• PKA: 9.43±0.30(Predicted)
• CAS DataBase Reference: Phenol, 2-[1-(1H-imidazol-1-yl)-2-(methylthio)ethenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 2-[1-(1H-imidazol-1-yl)-2-(methylthio)ethenyl]-(138206-46-9)
• EPA Substance Registry System: Phenol, 2-[1-(1H-imidazol-1-yl)-2-(methylthio)ethenyl]-(138206-46-9)

Safety Data

• Hazardous Substances Data: 138206-46-9(Hazardous Substances Data)

Usage

General Description

Phenol, 2-[1-(1H-imidazol-1-yl)-2-(methylthio)ethenyl]- is a chemical compound that consists of a phenol molecule attached to a 1-(1H-imidazol-1-yl)-2-(methylthio)ethenyl group. Phenol, 2-[1-(1H-imidazol-1-yl)-2-(methylthio)ethenyl]- has potential application in pharmaceuticals and biological research, particularly in the field of cancer treatment and anti-inflammatory drugs. The imidazole group is known for its ability to bind to various proteins and enzymes, making this compound potentially useful in drug design and development. Additionally, the methylthio group may contribute to the compound's reactivity and pharmacological properties. Research into the specific uses and effects of this chemical compound is ongoing.

Upstream product

• 69-72-7 salicylic acid 
• 24276-77-5 bromomethyl methyl sulfide 
• 80282-49-1 1-(1-(2-hydroxyphenyl)-2-methanone)-1H-imidazole 
• 2491-36-3 2-(2-bromoacetyl)hydroxybenzene 
• 288-32-4 1H-imidazole 
• 56986-82-4 α,α-dibromo-o-hydroxyacetophenone 

Downstream Products

• 138206-59-4 (E)-1-<1-<2-(Hexyloxy)phenyl>-2-(methylthio)ethenyl>-1H-imidazole 
• 138206-57-2 1-[(E)-2-Methylsulfanyl-1-(2-propoxy-phenyl)-vinyl]-1H-imidazole 
• 130773-02-3 (E)-1-[2-methylthio-1-[2-(pentyloxy)phenyl]ethenyl]-1H-imidazole hydrochloride 
• 138206-85-6 1-[(Z)-1-(2-Hexyloxy-phenyl)-2-methylsulfanyl-vinyl]-1H-imidazole 
• 138206-84-5 1-[(Z)-2-Methylsulfanyl-1-(2-pentyloxy-phenyl)-vinyl]-1H-imidazole 
• 138206-83-4 1-[(Z)-1-(2-Butoxy-phenyl)-2-methylsulfanyl-vinyl]-1H-imidazole 
• 138206-63-0 1-{(E)-1-[2-(2,4-Dichloro-benzyloxy)-phenyl]-2-methylsulfanyl-vinyl}-1H-imidazole 
• 138206-50-5 (Z)-1-<1-(2-Hydroxyphenyl)-2-(methylthio)ethenyl>-1H-imidazole 
• 138206-62-9 1-[(E)-1-(2-Benzyloxy-phenyl)-2-methylsulfanyl-vinyl]-1H-imidazole 
• 138206-61-8 1-[(E)-2-Methylsulfanyl-1-(2-octyloxy-phenyl)-vinyl]-1H-imidazole 
• 130726-68-0 (E)-1-<2-(Methylthio)-1-<2-(pentyloxy)phenyl>ethenyl>-1H-imidazole 
• 138206-60-7 1-[(E)-1-(2-Heptyloxy-phenyl)-2-methylsulfanyl-vinyl]-1H-imidazole 
• 138206-56-1 1-[(E)-1-(2-Ethoxy-phenyl)-2-methylsulfanyl-vinyl]-1H-imidazole 
• 138206-55-0 1-[(E)-1-(2-Methoxy-phenyl)-2-methylsulfanyl-vinyl]-1H-imidazole 

Relevant articles and documents

Neticonazole hydrochloride preparation method

The invention discloses a neticonazole hydrochloride preparation method, which comprises: carrying out an acylation reaction on imidazole and o-hydroxybenzoic acid, carrying out a wittig reaction on the product of the acylation reaction and 1-halogenated dimethyl sulfide, carrying out a reaction on the product of the wittig reaction and 1-halogenated pentane in an inorganic alkali, and salifying the product of the reaction and hydrochloric acid to obtain the neticonazole hydrochloride. According to the present invention, the method can avoid the use of the methanethiol and thionyl chloride, has characteristics of environmental protection, mild reaction condition, simple operation, simple post-treatment and high product purity, and is suitable for industrial production.