1307381-31-2

Basic information

• Product Name: Spiro[piperidine-4,7'-[7H]thieno[2,3-c]pyran], 2'-chloro-4',5'-dihydro-
• Synonyms: Spiro[piperidine-4,7'-[7H]thieno[2,3-c]pyran], 2'-chloro-4',5'-dihydro-;2'-Chloro-4',5'-dihydrospiro[piperidine-4,7'-thieno[2,3-c]pyran]
• CAS NO: 1307381-31-2
• Molecular Formula: C11H14ClNOS
• Molecular Weight: 243.75296
• Mol File: 1307381-31-2.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: Spiro[piperidine-4,7'-[7H]thieno[2,3-c]pyran], 2'-chloro-4',5'-dihydro-(CAS DataBase Reference)
• NIST Chemistry Reference: Spiro[piperidine-4,7'-[7H]thieno[2,3-c]pyran], 2'-chloro-4',5'-dihydro-(1307381-31-2)
• EPA Substance Registry System: Spiro[piperidine-4,7'-[7H]thieno[2,3-c]pyran], 2'-chloro-4',5'-dihydro-(1307381-31-2)

Safety Data

• Hazardous Substances Data: 1307381-31-2(Hazardous Substances Data)

Usage

General Description

Spiro[piperidine-4,7'-[7H]thieno[2,3-c]pyran], 2'-chloro-4',5'-dihydro- is a chemical compound with a spiro ring system containing a piperidine ring and a thienopyran ring. It also contains a chlorine atom at the 2' position and is in the 4',5'-dihydro- state. Spiro[piperidine-4,7'-[7H]thieno[2,3-c]pyran], 2'-chloro-4',5'-dihydro- has potential pharmaceutical applications due to its unique molecular structure, including the potential to interact with biological systems. Its specific properties and potential uses would require further study and experimentation.

Upstream product

• 1283095-47-5 4′,5′-dihydrospiro[piperidine-4,7′-thieno[2,3-c]pyran] 
• 41979-39-9 4-piperidone hydrochloride 
• 6964-21-2 thiophen-3-yl-acetic acid 
• 13781-67-4 3-(2-hydroxyethyl)thiophene 
• 1307248-45-8 tert-butyl 2′-chloro-4′,5′-dihydrospiro-[piperidine-4,7′-thieno[2,3-c]pyran]-1-carboxylate 
• 1283095-48-6 tert-butyl-4′,5′-dihydro-1H-spiro[piperidine-4,7′-thieno[2,3-c]pyran]-1-carboxylate 

Downstream Products

• 1378389-67-3 2-(2-chlorophenylmethyl)-3-(2-chlorospiro[4,5-dihydrothieno[2,3-c]pyran-7,4'-piperidine]-1'-yl)-N,N-dimethylpropanamide 
• 1378390-39-6 tert-butyl 2-[(2-chlorophenyl)methyl]-3-(2-chlorospiro[4,5-dihydrothieno[2,3-c]pyran-7,4'-piperidine]-1'-yl)propanoate 
• 1378389-70-8 2-(2-chlorophenylmethyl)-3-(2-chlorospiro[4,5-dihydrothieno[2,3-c]pyran-7,4'-piperidine]-1'-yl)-N-methylpropanamide 
• 1378389-75-3 2-(2-fluorophenylmethyl)-3-(2-chlorospiro[4,5-dihydrothieno[2,3-c]pyran-7,4'-piperidine]-1'-yl)-N,N-dimethylpropanamide 
• 1378390-41-0 tert-butyl 2-[(2-fluorophenyl)methyl]-3-(2-chlorospiro[4,5-dihydrothieno[2,3-c]pyran-7,4'-piperidine]-1'-yl)propanoate 
• 1378389-77-5 2-(2-fluorophenylmethyl)-3-(2-chlorospiro[4,5-dihydrothieno[2,3-c]pyran-7,4'-piperidine]-1'-yl)-N-methylpropanamide 

Relevant articles and documents

Synthesis of an ORL-1 Receptor Antagonist via a Radical Bromination and Deoxyfluorination to Afford a gem-Difluorospirocycle

The development of a synthesis of an ORL-1 receptor antagonist is described. The key process improvements in the synthetic sequence include a multikilogram bromination process and the development of a convergent coupling strategy. The process improvements resulted in the production of the active pharmaceutical ingredient (API) on a multikilogram scale.