1307803-23-1Relevant academic research and scientific papers
Turnagainolides A and B, cyclic depsipeptides produced in culture by a Bacillus sp.: Isolation, structure elucidation, and synthesis
Li, Dehai,Carr, Gavin,Zhang, Yonghong,Williams, David E.,Amlani, Ashraf,Bottriell, Helen,Mui, Alice L.-F.,Andersen, Raymond J.
, p. 1093 - 1099 (2011/08/03)
Two new cyclic depsipeptides, turnagainolides A (1) and B (2), have been isolated from laboratory cultures of a marine isolate of Bacillus sp. The structures of 1 and 2, which are simply epimers at the site of macrolactonization, were elucidated by analysis of NMR data and chemical degradation. A total synthesis of the turnagainolides confirmed their structures. Turnagainolide B (2) showed activity in a SHIP1 activation assay. (Chemical Equation Presented).
