130790-60-2Relevant academic research and scientific papers
Oxidative cyclization of diols derived from 1,5-dienes: Formation of enantiopure cis-tetrahydrofurans by using catalytic osmium tetroxide; formal synthesis of (+)-cis-solamin
Donohoe, Timothy J.,Butterworth, Sam
, p. 4766 - 4768 (2007/10/03)
(Chemical Equation Presented) High yields and high levels of stereocontrol are observed in the oxidative cyclization of vicinal diols using catalytic amounts of a transition metal (see scheme; TFA = trifluoroacetic acid). The product stereochemistry is co
Total synthesis of thyrsiferyl 23-acetate, a specific inhibitor of protein phosphatase 2A and an anti-leukemic inducer of apoptosis
Gonzalez, Isabel C.,Forsyth, Craig J.
, p. 9099 - 9108 (2007/10/03)
A convergent synthetic entry to the squalenoid polyether system has been developed and applied to the biologically active marine natural products thyrsiferyl 23-acetate (1a), thyrsiferol (1b), thyrsiferyl 18-acetate (1c), and thyrsiferyl 18,23-diacetate (
Total synthesis of (+)-curacin A, a marine cytotoxic agent
Hoemann, Michael Z.,Agrios, Konstantinos A.,Aube, Jeffrey
, p. 11087 - 11098 (2007/10/03)
The total synthesis of curacin A, a cytotoxic agent that interacts with the colchicine binding site on tubulin, is described. The convergent synthesis utilizes natural product and chiral pool starting materials (geraniol, serine) and asymmetric synthesis
CONVENIENT SYNTHESIS OF CHIRAL EPOXYISOPRENOIDS BY YEAST REDUCTION
Kodama, Mitsuaki,Minami, Hiroyuki,Mima, Yukiko,Fukuyama, Yoshiyasu
, p. 4025 - 4026 (2007/10/02)
The terminal double bond of acyclic isoprenoids was converted into chiral epoxide in high optical yield by using asymmetric reduction of α-ketol with baker's yeast.
