13080-75-6

Usage

Uses

5-Acetyl-10,11-dihydro-5H-dibenzo[b,f]azepine, is Dibenz[b,f]azepine derivative, possessing antioxidant potentials. It is also an analogue of Imipramine (I465980), and Desipramine (D290050). Carbamazepine Impurity 2.

Synthesis Reference(s)

Tetrahedron Letters, 9, p. 3469, 1968 DOI: 10.1016/S0040-4039(01)99085-9

InChI:InChI=1/C16H15NO/c1-12(18)17-15-8-4-2-6-13(15)10-11-14-7-3-5-9-16(14)17/h2-9H,10-11H2,1H3

Upstream product

• 84803-67-8 3-amino-5-acetyl-10,11-dihydro-5H-dibenzazepine 
• 71-43-2 benzene 
• 256-96-2 dibenzoazepine 
• 64-19-7 acetic acid 
• 494-19-9 9,10-dihydrodibenzazepine 
• 75-36-5 acetyl chloride 
• 108-24-7 acetic anhydride 

Downstream Products

• 79752-03-7 3-nitro-5-acetyl-10,11-dihydro-5H-dibenzazepine 
• 494-19-9 9,10-dihydrodibenzazepine 
• 40583-88-8 11-ethyliminodibenzyl 
• 22965-11-3 4,5-Dioxo-4,5,11,12-tetrahydro-indolo<7,1-ab><1>benzazepin 
• 19579-83-0 5H-dibenzazepine-10(11H),11-dione 
• 25961-11-9 3-chloro-5-(3-dimethylaminopropyl)-10,11-dihydro-5H-dibenzo(6,5)azepine 
• 78816-60-1 3-Carbisopropoxyamino-5-β-chlorpropionyl-iminodibenzyl 
• 83275-55-2 ethyl (5-(3-(N,N-diethylamino)propanoyl)-10,11-dihydro-5H-dibenzo[b,f]azepin-3-yl)carbamate 
• 132900-42-6 3-carbethoxy-5-aminoacetyl-10,11-dihydro-5H-dibenzazepine 
• 134068-17-0 ethyl (5-(N-ethylglycyl)-10,11-dihydro-5H-dibenzo[b,f]azepin-3-yl)carbamate 
• 78816-40-7 3-carbethoxyamino-10,11-dihydro-5H-dibenzazepine 
• 10464-35-4 3-amino-10,11-dihydro-5H-dibenzazepine 
• 84803-67-8 3-amino-5-acetyl-10,11-dihydro-5H-dibenzazepine 
• 64-17-5 ethanol 

Relevant academic research and scientific papers

SELECTIVE INHIBITORS OF CONSTITUTIVE ANDROSTANE RECEPTOR

The compounds of the invention are antagonists of CAR, with specificity for CAR over other proteins including PXR. The disclosed compounds are useful in treating or controlling cell proliferative disorders, in particular oncological disorders, such as cancer. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

A novel porphyrazine ligand tailored to homogeneous metal catalyzed transformations

A novel centrosymmetric porphyrazine (Pz) 1 decorated with pyrazino-dibenzo[b,f]azepine units have been prepared via Linstead macrocyclization reaction of a dinitrile precursor. Accordingly, the peripheral azepine nitrogen offers a chemical handle for sub

Reduction of diaryl alkenes by hypophosphorous acid-iodine in acetic acid

A mixture of 50% aqueous H3PO2 and I2 (in catalytic amount) in HOAc efficiently reduces aryl alkenes to the corresponding alkanes in high yield. Addition of acetic anhydride to the medium results in ring-acetylation (or N-acetylation in the case of amines). H3PO2 costs only one-fifth as much as hydriodic acid on a mole basis and one mole of H3PO2 produces four moles of HI, resulting in a 20-fold cost advantage for H3PO2/I2 over aqueous HI as a source of HI.

3-Cyano-N-(N,N-dimethylaminopropyl)-iminodibenzyl and salts thereof

3-Cyano-N-(N,N-dimethylaminopropyl)-iminodibenzyl, and its salts, prepared, inter alia, by heating 3-cyano-iminodibenzyl-5-carboxylic acid (N,N-dimethylaminopropyl ester) are described. The end product and its salts are useful as antidepressants.