1308311-33-2

Upstream product

• 71032-10-5 (E)-ethyl 6-bromohex-2-enoate 
• 25542-62-5 6-bromo-hexanoic acid ethyl ester 
• 113558-65-9 (E)-6-bromohex-2-en-1-yl methyl carbonate 
• 1415356-89-6 (E)-6-bromohex-2-en-1-yl isobutyl carbonate 
• 1415356-91-0 (E)-(6-(4-methylphenylsulfonamido)hex-2-en-1-yl) methyl carbonate 
• 1415356-92-1 (E)-(6-(4-methylphenylsulfonamido)hex-2-en-1-yl) isobutyl carbonate 
• 71032-11-6 (E)-6-bromohex-2-en-1-ol 
• 107970-37-6 N-(hexa-4,5-dien-1-yl)-4-methylbenzenesulfonamide 
• 81097-24-7 N-tosyl-(4-pentenyl)amine 
• 40365-64-8 hexa-4,5-dien-1-ol 
• 5390-04-5 pent-1-yn-5-ol 
• 1067892-64-1 (E)-N-(6-hydroxyhex-4-enyl)-4-methylbenzenesulfonamide 
• 1311201-43-0 (E)-N-(6-(tert-butyldimethylsilyloxy)hex-4-enyl)-4-methylbenzenesulfonamide 
• 1311201-42-9 (E)-methyl 6-(tert-butyldimethylsilyloxy)hex-4-enyl(tosyl)carbamate 

Relevant academic research and scientific papers

Pd-Catalyzed Asymmetric Allylic Cycloaddition of N-Containing Allylic Carbonates with Isocyanates

An efficient method for the enantioselective synthesis of cyclic ureas has been developed through Pd-catalyzed asymmetric allylic cycloaddition of readily accessible nitrogen-containing allylic carbonates with isocyanates. By using a palladium complex in

Rhodium-Catalyzed Asymmetric Intramolecular Hydroamination of Allenes

The rhodium-catalyzed asymmetric intramolecular hydroamination of sulfonyl amides with terminal allenes is reported. It provides selective access to 5- and 6-membered N-heterocycles, scaffolds found in a large range of different bioactive compounds. Moreover, gram scale reactions, as well as the application of suitable product transformations to natural products and key intermediates thereof are demonstrated.

Method of manufacturing compds. Allylnaphthol

PROBLEM TO BE SOLVED: To provide a method for producing allyl compounds by dehydrative allylation of allyl alcohols and the like in the presence of a catalyst system consisting of a catalyst precursor and a ligand. SOLUTION: In the method for producing allyl compounds: the catalyst precursor consisting of a complex compound having a ruthenium atom is mixed with an (S, S) or (R, R) type ligand having a specific structure; and then, the allyl alcohols and a substrate are mixed to be reacted with each other. In the allyl alcohols: a carbon atom and a hydrogen atom are connected to a carbon atom in the third position or a carbon atom is connected to a carbon atom in the first position; and these carbon atoms are sp2or sp hybridized carbon atoms or these carbon atoms are connected to carbon atoms only. The substrate is a cyclic compound having carbonyl groups in the first and third positions and having a carbon atom in the second position wherein the carbon atom is connected to a carbon atom or a hydrogen atom. COPYRIGHT: (C)2013,JPO&INPIT

Enantioselective synthesis of N-heterocycles via intramolecular Pd(0)-catalysed allylic amination

An efficient and stereoselective synthesis of pyrrolidine-, piperidine-, and azepane-type N-heterocycles is described by the intramolecular Pd(0)-catalysed cyclisation of amino allylic carbonates. The use of chiral ligands gave the corresponding heterocyclic derivatives having er values that were from moderate to good.

Asymmetric dehydrative C-, N-, and O-allylation using Naph-diPIM-dioxo-i- Pr-CpRu/p-TsOH combined catalyst

(S,S)- or (R,R)-Naph-diPIM-dioxo-i-Pr-CpRu(II) complex with a Bronsted acid catalyzes dehydrative intermolecular C-allylation with high enantio- and regioselectivity. The new soft Ru/hard H+ combined catalyst can also be used for intramolecular C-, N-, and O-allylations, giving nearly enantiomerically pure α-alkenyl-substituted cyclic compounds. As water is only the co-product, the synthetic process can be readily scaled up. Georg Thieme Verlag Stuttgart New York.

Asymmetric synthesis of optically active 2-vinylpyrrolidines and 2-vinylpiperidines by palladium-catalysed cyclisation of amino allylic carbonates

Optically active 2-vinylpyrrolidines and 2-vinylpiperidines were synthesised from the corresponding amino allylic carbonates via palladium-catalysed cyclisation. The use of chiral ligands gave the corresponding pyrrolidine and piperidine derivatives havin

A chiral bidentate sp2-N ligand, naph-diPIM: Application to CpRu-catalyzed asymmetric dehydrative C-, N-, and O-allylation

A handy new ligand: The CpRu complex (Cp=cyclopentadienyl) of a new type of chiral bisamidine ligand with a naphtho[1,2-b:7,8-b]dipyrroloimidazole (Naph-diPIM) skeleton with a Bronsted acid efficiently catalyzes dehydrative intermolecular C-allylation with high enantio- and regioselectivity. The catalytic system also gives nearly enantiomerically pure cycloalkanes and N- and O-heterocycles with a substrate/catalyst ratios of up to 10 000.