130837-17-1

Basic information

• Product Name: <2-<<1-methyl-1-(trimethylsilyl)ethyl>sulphonyl>phenyl>trimethylsilane
• CAS NO: 130837-17-1
• Molecular Weight: 328.623
• Mol File: 130837-17-1.mol

Chemical Properties

• CAS DataBase Reference: <2-<<1-methyl-1-(trimethylsilyl)ethyl>sulphonyl>phenyl>trimethylsilane(CAS DataBase Reference)
• NIST Chemistry Reference: <2-<<1-methyl-1-(trimethylsilyl)ethyl>sulphonyl>phenyl>trimethylsilane(130837-17-1)
• EPA Substance Registry System: <2-<<1-methyl-1-(trimethylsilyl)ethyl>sulphonyl>phenyl>trimethylsilane(130837-17-1)

Safety Data

• Hazardous Substances Data: 130837-17-1(Hazardous Substances Data)

Upstream product

• 108-98-5 thiophenol 
• 3019-20-3 isopropylthiobenzene 
• 75-77-4 chloro-trimethyl-silane 
• 4238-09-9 phenyl isopropyl sulfone 

Relevant articles and documents

METALATION REACTIONS. PART XVII. DILITHIATION OF PHENYL ISOPROPYL SULPHONE

The general utility of dimetalation reactions of phenyl iso-propyl sulphone for the preparation of ortho,alpha-substituted aryl sulphones is described.All the products were obtained in satisfactory yields. Key words: Alkyl aryl sulphones; metalation; poly

Scope and limitations in the use of α-silyl and α-stannyl sulfones as latent α-sulfonyl anions

Three methods for the regeneration of α-sulfonyl anions from α-silyl sulfones and α-stannyl sulfones are investigated. These methods include: (1) treatment of α-silyl sulfones with electrophiles (aldehydes and acid halides) in the presence of fluoride ion; (2) reaction of α-silyl sulfones with n-butyllithium which produces an α-silyl anion via a migration of the -SiMe3 group from the α-position to the ortho-position of the phenyl sulfones; and (3) direct transmetalation of α-stannyl sulfone by treatment with n-butyllithium. The addition of cerium [III] chloride is shown to substantially decrease enolization problems associated with addition of α-sulfonyl anions to carbonyl compounds bearing enolizable protons.