1308732-47-9Relevant academic research and scientific papers
Quinine as an organocatalytic dual activator for the diastereoselective synthesis of spiro-epoxyoxindoles
Chouhan, Mangilal,Pal, Anang,Sharma, Ratnesh,Nair, Vipin A.
, p. 7119 - 7123 (2013/12/04)
A highly efficient organocatalytic approach has been developed for the diastereoselective epoxidation of (E)-3-ylidene-indolin-2-one derivatives using readily available natural product quinine and urea-hydrogen peroxide (UHP) in DCM at 10 C to afford trans spiro-epoxyoxindoles which were further utilized to obtain β-hydroxy-α-amino esters by water mediated regioselective ring opening from the less hindered end with aniline derivatives, under sonication.
Chemoselective reduction of isatin-derived electron-deficient alkenes using alkylphosphanes as reduction reagents
Cao, Shu-Hua,Zhang, Xiu-Chun,Wei, Yin,Shi, Min
supporting information; experimental part, p. 2668 - 2672 (2011/06/25)
Under mild reaction conditions, the C=C double bond inisatin-derived electron-deficient alkenes has been exclusively reduced in the presence of alkylphosphanes and water to afford the corresponding reduction products in good to excellent yields. A plausib
