13088-15-8

Basic information

• Product Name: Propanedioic acid, [2-nitro-4-(trifluoromethyl)phenyl]-, diethyl ester
• CAS NO: 13088-15-8
• Molecular Formula: C14H14F3NO6
• Molecular Weight: 349.263
• Mol File: 13088-15-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Propanedioic acid, [2-nitro-4-(trifluoromethyl)phenyl]-, diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Propanedioic acid, [2-nitro-4-(trifluoromethyl)phenyl]-, diethyl ester(13088-15-8)
• EPA Substance Registry System: Propanedioic acid, [2-nitro-4-(trifluoromethyl)phenyl]-, diethyl ester(13088-15-8)

Safety Data

• Hazardous Substances Data: 13088-15-8(Hazardous Substances Data)

Upstream product

• 121-17-5 2-chloro-3-nitro-5-trifluoromethylbenzene 
• 105-53-3 diethyl malonate 
• 349-03-1 1-bromo-4-trifluoromethyl-2-nitrobenzene 

Downstream Products

• 1735-89-3 6-trifluoromethyl-2-indolinone 
• 880557-77-7 diethyl 2-(2-amino-4-(trifluoromethyl)phenyl)malonate 

Relevant articles and documents

Preparative method for carboxylic acids

A preparative method for carboxylic acids is disclosed in the present invention. The method is characterized in that: compounds (II) are reacted in the presence of hydrogen peroxide and base to produce target products (I), as represented by the following reaction scheme: wherein R1 is aryl, pyridyl, pyrimidyl, pyridazinyl, pyrazinyl, benzothienyl, benzofuranyl, quinolinyl, isoquinolinyl, thiadiazolyl, C1-6 alkyl, C3-6 cycloalkyl, C2-6 alkenyl, C2-6 alkynyl and hydrogen; R2 is alkoxycarbonyl, alkylaminocarbonyl, aminocarbonyl, alkylthiolcarbonyl, cyano, sulfonyl, sulfinyl, carbonyl, aldehyde, carboxyl, nitro, alkyl and hydrogen; R3 is alkoxycarbonyl, alkyl amido carbonyl, aminocarbonyl, cyano, sulfonyl, sulfinyl, carbonyl, carboxyl and nitro. The present invention has the following main benefits: cheap and readily available starting materials, safe processes, high yield, good quality, which facilitates industrial production.