130896-42-3

Upstream product

• 73636-64-3 di-l-menthyl malonate 
• 100-52-7 benzaldehyde 
• 131348-66-8 dimenthyl malonate 

Downstream Products

• 130896-44-5 ((3S,5S)-4-Hydroxymethyl-2,3,5-triphenyl-isoxazolidin-4-yl)-methanol 
• 1070251-50-1 bis((1S,2R,5S)-2-isopropyl-5-methylcyclohexyl) 2-((S)-phenyl(4,4,5,5-tetramethyl-1,3-dioxolan-2-yl)methyl)malonate 
• 155306-00-6 1,1-di-(-)-menthyl oxomalonate 

Relevant academic research and scientific papers

Chemoselective conjugate addition of dimethylzinc-mediated ether and acetal radicals to alkylidenemalonates and asymmetric reactions

(Chemical Equation Presented) Cyclic and acyclic ether or acetal radicals were generated directly from ethers or acetals by the action of dimethylzinc-air, and their subsequent conjugate addition reaction with alkylidenemalonates afforded the corresponding conjugate adducts in reasonably high yields. The reaction with benzylidenemalonates bearing formyl and imino groups gave chemoselectively the conjugate addition products. The asymmetric reaction of bis(8-phenylmenthyl) benzylidenemalonate proceeded diastereoselectively to provide the adduct with 93:7 dr.

1,3-DIPOLAR CYCLOADDITION OF DI-1-MENTHYL BENZYLIDENEMALONATE TO (Z)-N,α-DIPHENYLNITRONE: EXPLANATION FOR DIASTEREOSELECTIVITY

1,3-Dipolar cycloaddition of di-1-menthyl benzylidenemalonate to (Z)-N,α-diphenylnitrone proceeds by Si-face preference to give the endo-adduct as the major product among all four possible adducts.An explanation for this diastereofacial selectivity (Si-fa