1309366-09-3

Basic information

• Product Name: (2-bromo-3-methylphenyl)(pyrrolidin-1-yl)methanone
• Synonyms: (2-bromo-3-methylphenyl)(pyrrolidin-1-yl)methanone;1-(2-Bromo-3-methylbenzoyl)pyrrolidine
• CAS NO: 1309366-09-3
• Molecular Formula: C₁₂H₁₄BrNO
• Molecular Weight: 268.16
• Mol File: 1309366-09-3.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (2-bromo-3-methylphenyl)(pyrrolidin-1-yl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (2-bromo-3-methylphenyl)(pyrrolidin-1-yl)methanone(1309366-09-3)
• EPA Substance Registry System: (2-bromo-3-methylphenyl)(pyrrolidin-1-yl)methanone(1309366-09-3)

Safety Data

• Hazardous Substances Data: 1309366-09-3(Hazardous Substances Data)

Usage

General Description

The chemical compound (2-bromo-3-methylphenyl)(pyrrolidin-1-yl)methanone is a synthetic organic compound that is commonly used in research and drug development. It is a ketone derivative with a pyrrolidin-1-yl functional group attached to a 2-bromo-3-methylphenyl ring. (2-bromo-3-methylphenyl)(pyrrolidin-1-yl)methanone is known for its potential pharmacological properties and is often studied for its potential use in medical treatments. It may also have applications in the field of neuroscience and the study of neurological disorders. However, as with any chemical compound, (2-bromo-3-methylphenyl)(pyrrolidin-1-yl)methanone should be handled with care and in accordance with proper safety protocols.

Upstream product

• 123-75-1 pyrrolidine 
• 53663-39-1 3-methyl-2-bromobenzoic acid 
• 121794-40-9 2-bromo-3-methylbenzoic acid chloride 

Downstream Products

• 1319194-61-0 (2-(2-amino-7-fluoro-3-morpholinoquinolin-6-yl)-3-methylphenyl)(pyrrolidin-1-yl)methanone 
• 1319194-22-3 (2-(2-amino-3-morpholinoquinolin-6-yl)-3-methylphenyl)(pyrrolidin-1-yl)methanone 
• 1319196-64-9 (2-(2-(4-methoxybenzylamino)-3-morpholinoquinolin-6-yl)-3-methylphenyl)(pyrrolidin-1-yl)methanone 
• 1319194-42-7 (2-(2-amino-3-(2-ethylmorpholino)quinolin-6-yl)-3-methylphenyl)(pyrrolidin-1-yl)methanone 
• 1319194-41-6 (R)-(2-(2-amino-3-(3-methylmorpholino)quinolin-6-yl)-3-methylphenyl)(pyrrolidin-1-yl)methanone 
• 1319194-82-5 (2-(2-amino-3-cyclopentenylquinolin-6-yl)-3-methylphenyl)(pyrrolidin-1-yl)methanone 
• 1319194-80-3 (2-(2-amino-3-((1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl)quinolin-6-yl)-3-methylphenyl)(pyrrolidin-1-yl)methanone 
• 1319197-40-4 4-amino-2'-methyl-6'-(pyrrolidine-1-carbonyl)biphenyl-3-carbaldehyde 
• 1319197-39-1 (4'-amino-3'-(hydroxymethyl)-6-methylbiphenyl-2-yl)(pyrrolidin-1-yl)methanone 
• 1309366-11-7 (E)-ethyl 3-(2-(tert-butylamino)-6-(2-methyl-6-(pyrrolidine-1-carbonyl)phenyl)quinolin-3-yl)-2-methylacrylate 
• 1309366-13-9 (E)-3-(2-(tert-butylamino)-6-(2-methyl-6-(pyrrolidine-1-carbonyl)phenyl)quinolin-3-yl)-N,2-dimethylacrylamide 
• 1309363-72-1 3-(2-amino-6-(2-methyl-6-(pyrrolidine-1-carbonyl)phenyl)quinolin-3-yl)-N,2-dimethylpropanamide 
• 1309366-12-8 (E)-3-(2-(tert-butylamino)-6-(2-methyl-6-(pyrrolidine-1-carbonyl)phenyl)quinolin-3-yl)-2-methylacrylic acid 

Relevant articles and documents

AMINO HETEROARYL COMPOUNDS AS BETA-SECRETASE MODULATORS AND METHODS OF USE

The present invention comprises a new class of compounds useful for the modulation of Beta-secretase enzyme activity and for the treatment of Beta-secretase mediated diseases, including Alzheimer's disease (AD) and related conditions. In one embodiment, the compounds have a general Formula (I); wherein ring A, B1, B2, B3, L, R1, R2, ring Z, m and n of Formula I are defined herein. The invention also includes use of these compounds in pharmaceutical compositions for treatment, prophylactic or therapeutic, of disorders and conditions related to the activity of beta-secretase protein. Such disorders include, for example, Alzheimer's Disease (AD), cognitive deficits, cognitive impairment, schizophrenia and other central nervous system conditions related to and/or caused by the formation and/or deposition of plaque on the brain. The invention also comprises further embodiments of Formula (I), intermediates and processes useful for the preparation of compounds of Formula (I).