53663-39-1

Basic information

• Product Name: 2-Bromo-3-methylbenzoic acid
• Synonyms: 2-BROMO-3-METHYLBENZOIC ACID;3-methyl-2-bromobenzoic acid;2-Bromo-m-toluic acid;2-Bromo-3-methyl;2-Bromo-m-toluic acid (COOH=1);2-Bromo-3-methylbenzoic acid,97%;2-Bromo-3-methylbenz;2-Bromo-3-carboxytoluene
• CAS NO: 53663-39-1
• Molecular Formula: C₈H₇BrO₂
• Molecular Weight: 215.04
• Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Carboxylic Acids;Phenyls & Phenyl-Het;Benzoic acid;Organic acids;Acids & Esters;Bromine Compounds;Carboxylic Acids;Phenyls & Phenyl-Het;C8;Carbonyl Compounds;Building Blocks;Carbonyl Compounds;Chemical Synthesis;Organic Building Blocks
• Mol File: 53663-39-1.mol
• Article Data: 3

Chemical Properties

• Melting Point: 135-138 °C(lit.)
• Boiling Point: 308.3°Cat760mmHg
• Flash Point: 140.2°C
• Appearance: Off-white/Powder
• Density: 1.599g/cm³
• Vapor Pressure: 0.000297mmHg at 25°C
• Refractive Index: 1.595
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: soluble in Methanol
• PKA: 2.92±0.10(Predicted)
• CAS DataBase Reference: 2-Bromo-3-methylbenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromo-3-methylbenzoic acid(53663-39-1)
• EPA Substance Registry System: 2-Bromo-3-methylbenzoic acid(53663-39-1)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 22-24/25-37-26
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 53663-39-1(Hazardous Substances Data)

Usage

Chemical Properties

Off-white powder

Uses

2-Bromo-3-methylbenzoic acid may be used to synthesize N-phenyl-3-methylanthranilic acid via copper-catalyzed amination reaction with aniline.

General Description

2-Bromo-4-nitrotoluene is formed as an intermediate during the synthesis of 2-bromo-3-methylbenzoic acid. 2-Bromo-3-methylbenzoic acid can be obtained from 2-bromo-4-nitrotoluene via Von-Richter reaction.

InChI:InChI=1/C8H7BrO2/c1-5-3-2-4-6(7(5)9)8(10)11/h2-4H,1H3,(H,10,11)

Upstream product

• 66790-58-7 2-bromo-1-(bromomethyl)-3-methylbenzene 
• 4389-45-1 3-methylantranilic acid 
• 576-22-7 2-Bromo-m-xylene 
• 124-38-9 carbon dioxide 
• 61563-25-5 2,3-dibromotoluene 
• 109179-31-9 2-bromo-3-methyl-benzaldehyde 
• 7745-93-9 2-bromo-4-nitrotoluene 
• 151-50-8 potassium cyanide 

Downstream Products

• 121794-40-9 2-bromo-3-methylbenzoic acid chloride 
• 54879-20-8 2-bromo-3-methylaniline 
• 131001-86-0 methyl 2-bromo-3-methylbenzoate 
• 40961-11-3 N-phenyl-3-methylanthranilic acid 
• 291289-66-2 Benzyl-3-methyl-2-bromobenzoate 
• 924660-38-8 N-benzyl-2-bromo-3-methylbenzamide 
• 121794-43-2 2-Bromo-3-methyl-benzoic acid 2-hydroxy-ethyl ester 
• 121794-44-3 2-Bromo-3-methyl-benzoic acid 3-hydroxy-propyl ester 
• 121794-45-4 2-Bromo-3-methyl-benzoic acid 4-hydroxy-butyl ester 
• 121794-39-6 1-(2-Carboxy-6-methyl-phenyl)-naphthalene-2-carboxylic acid 
• 121794-18-1 1-Bromo-naphthalene-2-carboxylic acid 2-(2-bromo-3-methyl-benzoyloxy)-ethyl ester 
• 121794-19-2 1-Bromo-naphthalene-2-carboxylic acid 3-(2-bromo-3-methyl-benzoyloxy)-propyl ester 
• 121794-20-5 1-Bromo-naphthalene-2-carboxylic acid 4-(2-bromo-3-methyl-benzoyloxy)-butyl ester 
• 1268335-68-7 (E)-2-bromo-3-(3-oxobut-1-enyl)benzyl acetate 

Relevant articles and documents

METHOD FOR PRODUCING TETRAZOLINONE COMPOUND

A tetrazolinone compound represented by formula (1): [in the formula, R1 represents an alkyl group having 1-6 carbon atoms or the like] can be produced by reacting a compound represented by formula (2): [in the formula, X1 represents

Selective Oxidation of 2-Bromo-m-xylene to 2-Bromo-3-methylbenzoic Acid or 2-Bromoisophthalic Acid

Aqueous sodium dichromate oxidation of 2-bromo-m-xylene (1) under a carbon dioxide pressure gave 2-bromoisophthalic acid (58percent), while NBS-bromination of 1 followed by Sommelet oxidation to aldehyde and then potassium permanganate oxidation enabled t