53663-39-1

Usage

Uses

Used in Pharmaceutical Industry:
2-Bromo-3-methylbenzoic acid is used as a synthetic intermediate for the production of N-phenyl-3-methylanthranilic acid, which is achieved through a copper-catalyzed amination reaction with aniline. This synthesized compound has potential applications in the development of pharmaceuticals.
Used in Chemical Synthesis:
In the field of chemical synthesis, 2-Bromo-3-methylbenzoic acid is utilized as a key intermediate in the preparation of various organic compounds, contributing to the diversity of chemical products and their applications across different industries.

InChI:InChI=1/C8H7BrO2/c1-5-3-2-4-6(7(5)9)8(10)11/h2-4H,1H3,(H,10,11)

Upstream product

• 576-22-7 2-Bromo-m-xylene 
• 4389-45-1 3-methylantranilic acid 
• 66790-58-7 2-bromo-1-(bromomethyl)-3-methylbenzene 
• 124-38-9 carbon dioxide 
• 61563-25-5 2,3-dibromotoluene 
• 109179-31-9 2-bromo-3-methyl-benzaldehyde 
• 7745-93-9 2-bromo-4-nitrotoluene 
• 151-50-8 potassium cyanide 

Downstream Products

• 66790-60-1 3-(2-bromo-3-methylphenyl)propionic acid 
• 131001-86-0 methyl 2-bromo-3-methylbenzoate 
• 1086429-87-9 2-bromo-3-(bromomethyl)benzonitrile 
• 750585-94-5 2-bromo-3-formyl-benzoic acid methyl ester 
• 1269411-37-1 C₁₂H₁₅BrO₃ 
• 1268335-57-4 2-bromo-3-formylbenzyl acetate 
• 1268335-59-6 2-bromo-3-(4-hydroxybutyl)benzyl acetate 
• 1268335-60-9 2-bromo-3-(4-oxobutyl)benzyl acetate 
• 1268335-61-0 4-(3-(acetoxymethyl)-2-bromophenyl)butanoic acid 
• 1268335-62-1 methyl 4-(3-(acetoxymethyl)-2-bromophenyl)butanoate 
• 1268335-63-2 methyl 4-(3-(acetoxymethyl)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)butanoate 
• 1268335-56-3 2-bromo-3-cyanobenzyl acetate 
• 1268335-69-8 2-bromo-3-(3-oxobutyl)benzyl acetate 
• 1268335-70-1 3-(3-oxobutyl)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl acetate 

Relevant academic research and scientific papers

METHOD FOR PRODUCING TETRAZOLINONE COMPOUND

A tetrazolinone compound represented by formula (1): [in the formula, R1 represents an alkyl group having 1-6 carbon atoms or the like] can be produced by reacting a compound represented by formula (2): [in the formula, X1 represents

Halogen-metal exchange of 3-substituted 1,2-dibromoarenes: The use of long-range JCH coupling constants to determine regiochemistry

Regioselective halogen/metal exchange reactions were carried out on a series of 3-substituted-1,2-dibromoarenes. Product mixtures were quenched with CO2 to form the corresponding benzoic acid analogs to facilitate HPLC and NMR analysis. Substitution at the 3-position could readily be assigned on the basis of 2D HMBC long-range correlations, while assignment at the 2-position was not as straightforward. The use of three-bond JCH coupling constant measurements, extracted from 1-D 1H coupled 13C experiments, were necessary to render unequivocal regio assignments. Copyright

Selective Oxidation of 2-Bromo-m-xylene to 2-Bromo-3-methylbenzoic Acid or 2-Bromoisophthalic Acid

Aqueous sodium dichromate oxidation of 2-bromo-m-xylene (1) under a carbon dioxide pressure gave 2-bromoisophthalic acid (58percent), while NBS-bromination of 1 followed by Sommelet oxidation to aldehyde and then potassium permanganate oxidation enabled t