130954-49-3Relevant academic research and scientific papers
A Photoannulation Route to Naphthalenes from Cyclic Ketones
Olsen, Robert J.,Minniear, John C.,Overton, W. Mack,Sherrick, John M.
, p. 989 - 991 (1991)
A three-step annulation of cyclic ketones has been developed.Aldol condensation with an aromatic aldehyde followed by Wittig olefination produces a 1,3-diene, which undergoes oxidative photocyclization to produce a naphthalene derivative.Ketone ring sizes of C5 to C8 were annulated successfully.The sequence was also applied successfully to three methyl-substituted derivatives and one polycyclic case.
