1309658-29-4Relevant academic research and scientific papers
Catalytic asymmetric synthesis of trisubstituted aziridines
Huang, Li,Wulff, William D.
, p. 8892 - 8895 (2011/08/04)
A method is described which provides for the direct asymmetric catalytic synthesis of trisubstituted aziridines from imines and diazo compounds. While unactivated imines were not reactive to α-diazo carbonyl compounds in which the diazo carbon was disubstituted, N-Boc imines react with both α-diazo esters and α-diazo-N-acyloxazolidinones to give trisubstituted aziridines with excellent diastereo- and enantioselectivities.
Chiral Bronsted acid-catalyzed asymmetric trisubstituted aziridine synthesis using α-diazoacyl oxazolidinones
Hashimoto, Takuya,Nakatsu, Hiroki,Yamamoto, Kumiko,Maruoka, Keiji
supporting information; experimental part, p. 9730 - 9733 (2011/09/13)
Despite the remarkable advances in catalytic asymmetric aziridinations over the past decades, establishing a general procedure for the stereoselective synthesis of trisubstituted aziridines has remained an elusive goal. Chiral N-triflyl phosphoramide-cata
