1309675-39-5

Basic information

• Product Name: 1-benzyl 4-ethyl (2S)-2-((3S)-3-hydroxy-5-(trimethylsilyl)pent-4-ynoyl)-2-((triethylsilyl)oxy)succinate
• CAS NO: 1309675-39-5
• Molecular Weight: 534.797
• Mol File: 1309675-39-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-benzyl 4-ethyl (2S)-2-((3S)-3-hydroxy-5-(trimethylsilyl)pent-4-ynoyl)-2-((triethylsilyl)oxy)succinate(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyl 4-ethyl (2S)-2-((3S)-3-hydroxy-5-(trimethylsilyl)pent-4-ynoyl)-2-((triethylsilyl)oxy)succinate(1309675-39-5)
• EPA Substance Registry System: 1-benzyl 4-ethyl (2S)-2-((3S)-3-hydroxy-5-(trimethylsilyl)pent-4-ynoyl)-2-((triethylsilyl)oxy)succinate(1309675-39-5)

Safety Data

• Hazardous Substances Data: 1309675-39-5(Hazardous Substances Data)

Upstream product

• 105-36-2 ethyl bromoacetate 
• 443988-54-3 benzyl 2-triethylsilyl-2-oxoacetate 

Downstream Products

• 1309675-40-8 1-benzyl 4-ethyl (2S)-2-((1R,3S)-1,3-dihydroxy-5-(trimethylsilyl)pent-4-yn-1-yl)-2-((triethylsilyl)oxy)succinate 

Relevant articles and documents

Formal synthesis of leustroducsin B via Reformatsky/Claisen condensation of silyl glyoxylates

A formal synthesis of leustroducsin B has been completed. The synthesis relies upon a recently developed Reformatsky/Claisen condensation of silyl glyoxylates and enantioenriched β-lactones that establishes two of the molecule's three core stereocenters and permits further elaboration to an intermediate in Imanishi's synthesis via reliable chemistry (Prasad reduction, asymmetric pentenylation, Mitsunobu inversion).