130981-12-3 Usage
General Description
"(1R,2S)-2-(tert-butoxycarbonylamino)cyclopentanecarboxylic acid" is a relatively complex, specialty chemical. As suggested by its name, it features a cyclopentane ring, which is a cyclic molecule with five carbon atoms. It includes a tert-butoxycarbonylamino group, often abbreviated as Boc-amino, which is a common protective group for amines in organic synthesis. It also includes a carboxylic acid group, indicating the presence of both a carbonyl (C=O) and a hydroxyl (OH) group on one carbon atom. The specific designation of (1R,2S) refers to the configuration of these functional groups within the molecule, based on established conventions of stereochemistry. Though its specific uses are not broadly documented, similar molecules with cyclopentane ring are often used in pharmaceutical and material science research.
Check Digit Verification of cas no
The CAS Registry Mumber 130981-12-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,0,9,8 and 1 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 130981-12:
(8*1)+(7*3)+(6*0)+(5*9)+(4*8)+(3*1)+(2*1)+(1*2)=113
113 % 10 = 3
So 130981-12-3 is a valid CAS Registry Number.
InChI:InChI=1/C11H19NO4/c1-11(2,3)16-10(15)12-8-6-4-5-7(8)9(13)14/h7-8H,4-6H2,1-3H3,(H,12,15)(H,13,14)/t7-,8+/m1/s1
130981-12-3Relevant articles and documents
Synthesis of enantiomerically pure cis and trans 2-aminocyclopentanecarboxylic acids. Use of proline replacements in potential HIV-protease inhibitors
Noeteberg, Daniel,Branalt, Jonas,Kvarnstroem, Ingemar,Classon, Bjoern,Samuelsson, Bertil,Nillroth, Ulrika,Danielson, U. Helena,Karlen, Anders,Hallberg, Anders
, p. 7975 - 7984 (1997)
The synthesis of the four diastereomeric 2-aminocyclopentanecarboxylic acids, their use as replacements for proline in potential HIV protease inhibitors containing a hydroxyethylamine dipeptide isostere and the evaluation of the biological activity of these is described.
Synthesis of Cyclic and Acyclic β-Amino Acids via Chelation-Controlled 1,3-Dipolar Cycloaddition
Hanselmann, Roger,Zhou, Jiacheng,Ma, Philip,Confalone, Pat N.
, p. 8739 - 8741 (2007/10/03)
Isoxazolidines have been synthesized in diastereomeric excess up to 94% via a MgBr2-induced chelation-controlled 1,3-dipolar cycloaddition reaction with N-hydroxyphenylglycinol as a chiral auxiliary. The diastereomerically pure isoxazolidines were further transformed into cyclic and acyclic β-amino acid derivatives.
