1309855-76-2Relevant articles and documents
Discovery of potent nucleotide-mimicking competitive inhibitors of hepatitis C virus NS3 helicase
Gemma, Sandra,Butini, Stefania,Campiani, Giuseppe,Brindisi, Margherita,Zanoli, Samantha,Romano, Maria Pia,Tripaldi, Pierangela,Savini, Luisa,Fiorini, Isabella,Borrelli, Giuseppe,Novellino, Ettore,Maga, Giovanni
, p. 2776 - 2779 (2011)
Among the enzymes involved in the life cycle of HCV, the non-structural protein NS3, with its double function of protease and NTPase/helicase, is essential for the virus replication. Exploiting our previous knowledge in the development of nucleotide-mimic