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Berberine, a naturally occurring bioactive alkaloid, is found in various plants such as barberry, tree turmeric, Oregon grape, and goldenseal. It has been utilized in traditional Chinese and Ayurvedic medicine for centuries due to its wide range of medicinal properties. Berberine is particularly known for its potent anti-inflammatory and antibacterial effects, and recent studies suggest that it may also aid in regulating blood sugar levels, managing cholesterol, and facilitating weight loss. However, it is important to be aware of its potential side effects and possible interactions with other medications.

131-10-2

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Basic information
1. Product Name: berbine
2. Synonyms: (S)-5,8,13,13a-Tetrahydro-6H-dibenzo[a,g]quinolizine;(-)-Berbine;(S)-7,8,13,14-Tetrahydroprotoberberine;(S)-Tetrahydroprotoberberine;C05204;alpha-berbine
3. CAS NO:131-10-2
4. Molecular Formula: C17H17N
5. Molecular Weight: 235.32
6. EINECS: N/A
7. Product Categories: N/A
8. Mol File: 131-10-2.mol
Chemical Properties
1. Melting Point: 85-86 ºC
2. Boiling Point: 354.2 °C at 760 mmHg
3. Flash Point: 151.8 °C
4. Appearance: /
5. Density: 1.17
6. Vapor Pressure: 3.41E-05mmHg at 25°C
7. Refractive Index: 1.662
8. Storage Temp.: N/A
9. Solubility: N/A
10. CAS DataBase Reference: berbine(CAS DataBase Reference)
11. NIST Chemistry Reference: berbine(131-10-2)
12. EPA Substance Registry System: berbine(131-10-2)
Safety Data
1. Hazard Codes: N/A
2. Statements: N/A
3. Safety Statements: N/A
4. WGK Germany:
5. RTECS:
6. HazardClass: N/A
7. PackingGroup: N/A
8. Hazardous Substances Data: 131-10-2(Hazardous Substances Data)

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131-10-2 Usage

Uses

Used in Traditional Medicine:
Berberine is used as a medicinal compound for its anti-inflammatory and antibacterial properties, which have been recognized and utilized in traditional Chinese and Ayurvedic medicine for centuries.
Used in Managing Blood Sugar Levels:
Berberine is used as a natural supplement for regulating blood sugar levels, potentially helping individuals with diabetes or those at risk of developing the condition.
Used in Cholesterol Management:
Berberine is used as a cholesterol-lowering agent, assisting in the management of cholesterol levels and contributing to cardiovascular health.
Used in Weight Loss:
Berberine is used as a weight loss aid, potentially facilitating weight loss by improving metabolic functions and reducing inflammation.
Used in Pharmaceutical Industry:
Berberine is used as an active pharmaceutical ingredient in the development of new drugs, leveraging its various medicinal properties for the treatment of different health conditions.
Used in Dietary Supplements:
Berberine is used as a dietary supplement, providing consumers with the potential health benefits associated with its anti-inflammatory, antibacterial, and metabolic effects.

Check Digit Verification of cas no

The CAS Registry Mumber 131-10-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,3 and 1 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 131-10:
(5*1)+(4*3)+(3*1)+(2*1)+(1*0)=22
22 % 10 = 2
So 131-10-2 is a valid CAS Registry Number.

InChI:InChI=1/C17H17N/c1-2-7-15-12-18-10-9-13-5-3-4-8-16(13)17(18)11-14(15)6-1/h1-8,17H,9-12H2/t17-/m0/s1

131-10-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name	α-berbine

1.2 Other means of identification

Product number	-
Other names	alpha-berbine

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:131-10-2 SDS

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131-10-2Downstream Products

131-10-2Related news

The Polonovski–Potier Reaction of berbine (cas 131-10-2) N-Oxides. Synthesis of 8-Hydroxymethyl and 8-Methylberbine (cas 131-10-2)s09/27/2019

The Polonovski–Potier reaction of trans and cis berbines N-oxides was studied. The 8-cyano derivative obtained from transN-oxides were used to synthesize 8-hydroxymethyl and 8-methyl berbines. This procedure was applied to the stereocontroled synthesis of (8R, 14S)-(−)-8-methylcanadine from (14...detailed

Ilicifoline: new berbine (cas 131-10-2) dimer alkaloid from Berberis ilicifolia09/26/2019

From Berberis ilicifolia, a new dimer is described, but this alkaloid is related to a bisberbine. It is the first dimer of this type in Berberis.detailed

4-Methylenedioxolan-2-ones as convenient synthons for the preparation of natural products of the berbine (cas 131-10-2) and calycotomine series09/25/2019

Intramolecular amidoalkylation of nonactivated 3-(2-arylethyl)-4-hydroxyoxazolidin-2-ones in polyphosphoric acid gave oxazolo[4,3-a]isoquinolin-3-one whose hydrolysis affords isoquinoline β-amino alcohols, calycotomine analogs. Using the developed procedure, 13,13,13a-trimethylberbine was synth...detailed

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