131003-39-9

Basic information

• Product Name: 2-Acetylamino-2-((E)-(S)-1,3-diphenyl-allyl)-malonic acid dimethyl ester
• CAS NO: 131003-39-9
• Molecular Weight: 381.428
• Mol File: 131003-39-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Acetylamino-2-((E)-(S)-1,3-diphenyl-allyl)-malonic acid dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Acetylamino-2-((E)-(S)-1,3-diphenyl-allyl)-malonic acid dimethyl ester(131003-39-9)
• EPA Substance Registry System: 2-Acetylamino-2-((E)-(S)-1,3-diphenyl-allyl)-malonic acid dimethyl ester(131003-39-9)

Safety Data

• Hazardous Substances Data: 131003-39-9(Hazardous Substances Data)

Upstream product

• 108-24-7 acetic anhydride 
• 95071-02-6 (R)-dimethyl 2-(1,3-diphenylallyl)malonate 
• 73930-97-9 3-acetoxy-1,3-diphenylpropene 
• 72071-39-7 dimethyl acetamidomalonate sodium salt 

Relevant articles and documents

Palladium-catalyzed asymmetric alkylation via II-allyl intermediate: Acetamidomalonate ester as a nucleophile

Asymmetric allylic alkylation of 1,3-diphenyl-2-propenyl acetate with sodium salt of acetamidomalonate ester has been carried out in the presence of a palladium catalyst containing (S)-BINAP to give a chiral α-allyl-α-acetamidomalonate ester derivative of high optical purity (94 ± 1% ee).