95071-02-6Relevant articles and documents
Chiral Phosphinoferrocenyl-Calixarenes
Karpus, Andrii,Yesypenko, Oleksandr,Boiko, Vyacheslav,Poli, Rinaldo,Daran, Jean-Claude,Voitenko, Zoia,Kalchenko, Vitaly,Manoury, Eric
, p. 3386 - 3394 (2016)
The Mitsunobu alkylation of 4-tert-butylcalix[4]arene with (S)-(2-diphenylthiophosphinoferrocenyl)methanol followed by desulfuration of the thiophosphine unit using tris(dimethylamino)phosphine afforded enantiomerically pure calixarene mono- and di(ferroc
A bidentate resorcinarene-based palladium carbene complex
Ngodwana, Lonwabo,Bose, Sritama,Smith, Vincent J.,Van Otterlo, Willem A. L.,Arnott, Gareth E.
, p. 1923 - 1929 (2017)
The synthesis and characterization of a distally bridged, bidentate resorcinarene bis(carbene) palladium complex is described for the first time. Preliminary catalytic studies show promise for future developments along this framework.
Enantioselective Reductive Homocoupling of Allylic Acetates Enabled by Dual Photoredox/Palladium Catalysis: Access to C2-Symmetrical 1,5-Dienes
Zhang, Hong-Hao,Tang, Menghan,Zhao, Jia-Jia,Song, Changhua,Yu, Shouyun
supporting information, p. 12836 - 12846 (2021/08/30)
Transition-metal-catalyzed reductive coupling reactions have emerged as powerful protocols to construct C-C bonds. However, the development of enantioselective C(sp3)-C(sp3) reductive coupling remains challenging. Herein, we report a highly regio-, diastereo-, and enantioselective reductive homocoupling of allylic acetates through cooperative palladium and photoredox catalysis using diisopropylethylamine or Hantzsch ester as a homogeneous organic reductant. This straightforward protocol enables the stereoselective construction of C(sp3)-C(sp3) bonds under mild reaction conditions. A series of C2-symmetrical chiral 1,5-dienes were easily prepared with excellent enantioselectivities (up to >99% ee), diastereoselectivities (up to >95:5 dr), and regioselectivities (up to >95:5 rr). The resultant chiral 1,5-dienes can be directly used as chiral ligands in asymmetric synthesis, and they can be also transformed into other valuable chiral ligands.
Chiral P,Olefin Ligands with Rotamers for Palladium-Catalyzed Asymmetric Allylic Substitution Reactions
Mino, Takashi,Yamaguchi, Daiki,Kumada, Manami,Youda, Junpei,Saito, Hironori,Tanaka, Junya,Yoshida, Yasushi,Sakamoto, Masami
supporting information, p. 532 - 538 (2021/03/09)
We synthesized a series of phosphine-olefin-type chiral aminophosphines, and we confirmed that these each exists as two rotamers at the C(aryl)-N(amine) bond. We also investigated the ability of these aminophosphines to act as chiral ligands for Pd-catalyzed asymmetric allylic substitution reactions, such as the alkylation of allylic acetates with malonates or indoles, and we found they gave high enantio-selectivities (up to 98% ee).