1310366-00-7

Basic information

• Product Name: N-(2-bromobenzenesulfonyl)-N-acetyloxy-acetamide
• Synonyms: N-(2-bromobenzenesulfonyl)-N-acetyloxy-acetamide
• CAS NO: 1310366-00-7
• Molecular Weight: 336.163
• Mol File: 1310366-00-7.mol

Chemical Properties

• CAS DataBase Reference: N-(2-bromobenzenesulfonyl)-N-acetyloxy-acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-bromobenzenesulfonyl)-N-acetyloxy-acetamide(1310366-00-7)
• EPA Substance Registry System: N-(2-bromobenzenesulfonyl)-N-acetyloxy-acetamide(1310366-00-7)

Safety Data

• Hazardous Substances Data: 1310366-00-7(Hazardous Substances Data)

Upstream product

• 1352414-77-7 N-(2-bromobenzenesulfonyl)-N-acetyloxy-2,2-dimethylacetamide 
• 1310366-15-4 tert-butyl N-(2-bromobenzenesulfonyl)-N-acetyloxy-carbamate 
• 1310366-71-2 N-acetyloxy-2-bromobenzenesulfonamide 
• 75-36-5 acetyl chloride 
• 1352414-89-1 N-hydroxy-N-acetyl-2-bromobenzenesulfonamide 
• 915403-74-6 C₁₁H₁₄BrNO₄S 
• 2905-25-1 o-bromobenzenesulfonyl chloride 

Downstream Products

• 1352414-77-7 N-(2-bromobenzenesulfonyl)-N-acetyloxy-2,2-dimethylacetamide 
• 1352414-78-8 N-(2-bromobenzenesulfonyl)-N-acetyloxy-2,2,2-trimethylacetamide 
• 1352414-80-2 N',N'-dimethyl-N-2-bromo-benzenesulfonyl-N-acetoxy-carbamide 
• 576-92-1 bromobenzene-2-sulfonic acid 
• 1310366-71-2 N-acetyloxy-2-bromobenzenesulfonamide 
• 64-19-7 acetic acid 

Relevant articles and documents

Optimization of HNO production from N, O - Bis -acylated hydroxylamine derivatives

A wide range of N,O-bis-acylated hydroxylamine derivatives with chloro or arenesulfonyl leaving groups, and a related set of N-hydroxy-N-acylsulfonamides, have been synthesized and evaluated for nitroxyl (HNO) production. Mechanistic studies have revealed that the observed aqueous chemistry is more complicated than originally anticipated, and have been used to develop a new series of efficient HNO precursors (4u-4x, 7c-7d) with tunable half-lives.

Bis-Acylated Hydroxylamine Derivatives

The invention provides certain bis-acylated hydroxylamine derivative compounds, pharmaceutical compositions and kits comprising such compounds, and methods of using such compounds or pharmaceutical compositions. In particular, the invention provides methods of using such compounds or pharmaceutical compositions for treating, preventing, or delaying the onset and/or develop of a disease or condition. In some embodiments, the disease or condition is selected from cardiovascular diseases, ischemia, reperfusion injury, cancerous disease, pulmonary hypertension and conditions responsive to nitroxyl therapy.